Osteoarthritis (OA) is a major cause of knee pain and knee replacement in older people. The disease is characterised by a progressive thinning and loss of cartilage until the exposed ends of bones in a joint rub together causing pain. Currently, there is no treatment to reduce the loss of cartilage associated with OA.
It is thought that some of aspirin properties may help preserve cartilage in knee joints and reduce the burden of OA. However, the effect of aspirin on OA is unproven.
What does participation involve?
An MRI (Magnetic Resonance Image) of a knee, undertaking questionnaires and recording physical activity for 7 days at enrolment into the ASPREE study. This will be repeated in 3-4 years.
Thank you to ASPREE participants involved in this study. Enrolments have now closed.
Can aspirin reduce cartilage loss associated with OA?
Collaboration:
- The Musculo-skeletal Unit at the School of Public Health and Preventive Medicine, Monash University
- Monash University Biomedical Imaging Centre (MBI)
- ASPREE GP co-investigators
Funding:
- Monash University