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ASPREE results summary
THE ASPREE PROJECT
Aspirin and Ageing Health Research
Populations around the world are ageing. The ASPREE project is a long-term multi-centre, bi-national study of aspirin and health in older adults, aiming to discover ways to maintain health, quality of life and independence as we age.
This landmark research has three components:
1) ASPREE (ASPirin in Reducing Events in the Elderly), a randomised, blinded, placebo-controlled clinical trial of low-dose (100mg) aspirin in healthy older adults. The trial’s ground-breaking findings underpin revised international aspirin prescribing guidelines.
2) ASPREE-XT (ASPREE – eXTension) study the first follow-up observational health phase of the study investigating long-lasting effects of low-dose aspirin on disease, such as cancer. Additionally, it investigated a broad range of factors that contribute to the maintenance of physical and cognitive health in older adults.
3) ASPREE-LT (ASPREE – Long Term), a second observational phase which continues long term follow up of the cohort with a particular focus on cancer and ageing health outcomes.
Findings from the ASPREE project advance the care and wellbeing of ageing adults around the world.
key facts
19,114
ASPREE Participants
All participants – 16,703 in Australia (aged 70+ years) and 2,411 in the U.S. (minorities aged 65+ years) – were free of dementia, significant physical disability and known cardiovascular disease at enrolment.
100%
Public funded
The ASPREE Project is funded by the Australian and U.S. governments and is led by Monash University in Australia and the Berman Centre for Outcomes and Clinical Research in the United States.
18 +
Specialty sub-studies
Thanks to the support of participants during the ASPREE project, multiple sub-studies have provided and will continue to provide, invaluable information on aspects of health and ageing.
KEY MILESTONES
ASPREE Trial Results
In September 2018, the ASPREE trial published results in three separate papers in one edition of the prestigious New England Journal of Medicine.
Translation into Care
The American College of Cardiology and American Heart Association adopted ASPREE findings into their revised primary prevention aspirin guidelines.
ASPREE-XT to ASPREE-LT
ASPREE-LT continues on from ASPREE-XT to support important research into the wide range of factors contributing to health in older age.
Page updated: 1 March 2021
LATEST NEWS
ASPREE enters its third phase – ASPREE-LT
We are pleased to share an update on the future of the ASPREE Study. With new funding from the...
ASPREE explores how social engagement and mentally stimulating activities are related to frailty risk
Recent research from ASPREE published in the journal GeroScience has found that socially and...
ASPREE study finds music can stave off dementia
Listening to music when you are over 70 years of age has been linked to a 39 per cent reduction in...