PUBLICATIONS

2024

• Zhou Z, Webb KL, Nelson MR, Woods RL, Ernst ME, Murray AM, Chan AT, Tonkin A, Reid CM, Orchard SG, Kirpach B, Shah RC, Stocks N, Broder JC, Wolfe R. Short- and long-term impact of aspirin cessation in older adults: a target trial emulation. BMC Med. 2024; Jul 29, doi: 10.1186/s12916-024-03507-8.
• Nelson MR, Black JA. Aspirin: latest evidence and developments. Heart [online]. 2024; Jul 29, doi: 10.1136/heartjnl-2024-323948.
• Clark DPQ, Zhou Z, Hussain SM, Tran C, Britt C, Storey E, Lowthian JA, Shah RC, Dillon H, Wolfe R, Woods RL, Rance G, McNeil JJ. Low-Dose Aspirin and Progression of Age-Related Hearing Loss: A Secondary Analysis of the ASPREE Randomized Clinical Trial. JAMA Netw Open. 2024; Jul 25, doi: 10.1001/jamanetworkopen.2024.24373.
• Descallar J, Ma J, Zhu H, Heritier S, Wolfe R. Cause-specific hazard Cox models with partly interval censoring – Penalized likelihood estimation using Gaussian quadrature. Statistical Methods in Medical Research. 2024; Jul 25, doi: 10.1177/09622802241262526.
• Xu E, Vanghelof J, Wang Y, Patel A, Furst J, Raicu DS, Neumann JT, Wolfe R, Gao CX, McNeil JJ, Shah RC, Tchoua R. Outcome risk model development for heterogeneity of treatment effect analyses: a comparison of non-parametric machine learning methods and semi-parametric statistical methods. BMC Med Res Methodol. 2024; Jul 23, doi: 10.1186/s12874-024-02265-8.
• Phyo AZZ, Espinoza SE, Murray AM, Fransquet PD, Wrigglesworth J, Woods RL, Ryan J. Epigenetic age acceleration and the risk of frailty, and persistent activities of daily living (ADL) disability, Age and Ageing. 2024; June 28, doi: 10.1093/ageing/afae127.
• Clayton-Chubb D, Majeed A, Roberts S, Schneider HG, Fitzpatrick J, Woods R, Hussain SM, Tan N, Commins I, Lubel JS, Tran C, Hodge A, McNeil J, Kemp W. SAT-464-YI Transaminases and older adults: distribution and associations with all-cause mortality. J Hepatol Online. 2024; Jun 18, doi: 10.1016/S0168-8278(24)01883-X.
• Teshale AB, Htun HL, Owen AJ, Ryan J, Baker JR, Vered M, Reid CM, Woods RL, Berk M, Tonkin A, Neumann JT, Kilkenny MF, Phyo AZZ, Nelson MR, Stocks N, Britt C, Freak-Poli R. Gender-specific aspects of socialisation and risk of cardiovascular disease among community-dwelling older adults: a prospective cohort study using machine learning algorithms and a conventional method. J Epidemiol Community Health. 2024; Jun 5, doi: 10.1136/jech-2023-221860 [epub ahead of print] PMID: 38839108.
• Robman LD, Wolfe R, Woods RL, Thao LTP, Makeyeva GA, Hodgson LAB, Lepham YA, Jachno K, Phung J, Maguire E, Luong H, Trevaks RE, Ward SA, Fitzgerald SM, Orchard SG, Lacaze P, Storey E, Abhayaratna WP, Nelson MR, Guymer RH, McNeil JJ. Effect of Low-Dose Aspirin on the Course of Age-Related Macular Degeneration: A Secondary Analysis of the ASPREE Randomized Clinical Trial. JAMA Ophthalmol. 2024; May 23, doi: 10.1001/jamaophthalmol.2024.1584 [epub ahead of print] PMID: 38780931; PMCID: PMC11117148.
• Bhatia HS, Becker RC, Leibundgut G, Patel M, Lacaze P, Tonkin A, Narula J, Tsimikas S. Lipoprotein(a), platelet function and cardiovascular disease. Nat Rev Cardiol. 2024; May 21, doi: 10.1038/s41569-023-00947-2 [epub 2023; Nov 8] PMID: 37938756.
• Vishwanath S, Hopper I, Cloud GC, Chong TT, Shah RC, Donnan GA, Williamson JD, Eaton CB, Wolfe R, Reid CM, Tonkin AM, Orchard SG, Fitzgerald S, Murray AM, Woods RL, Nelson MR, Sood A, Steves CJ, Ryan J. The impact of incident stroke on cognitive trajectories in later life. Alzheimers Res Ther. 2024; May 18, doi: 10.1186/s13195-024-01479-8 PMID: 38762556; PMCID: PMC11102228.
• Shah S, Chen Y, Owen A, Woods RL, Ryan J, Owen N, Wolfe R, Dunstan DW, Beck B, Britt C, Gasevic D. Walking for transport and all-cause mortality: a prospective cohort study of Australian community-dwelling older adults. BMJ Public Health. 2024; Apr 30, doi:10.1136/bmjph-2023-000709 (online).
• Tran C, Yeap BB, Ball J, Clayton-Chubb D, Hussain SM, Brodtmann A, Tonkin AM, Neumann JT, Schneider HG, Fitzgerald S, Woods RL, McNeil JJ. Testosterone and the risk of incident atrial fibrillation in older men: further analysis of the ASPREE study. EClinicalMedicine. 2024; Apr 29, doi: 10.1016/j.eclinm.2024.102611 PMID: 38707912; PMCID: PMC11067494.
• Forbes M, Lotfaliany M, Mohebbi M, Reynolds CF, Woods RL, Orchard S, Chong T, Agustini B, O’Neil A, Ryan J, Berk M. Depressive symptoms and cognitive decline in older adults. Int Psychogeriatr. 2024: Apr 16, doi: 10.1017/S1041610224000541 [epub ahead of print] PMID: 38623851.
• Htun HL, Teshale AB, Owen AJ, Ryan J, Woods RL, Orchard SG, Hajek A, Lysen T, Shah RC, Chong TTJ, Sheets KM, Joyce J, Murray AM, Freak-Poli R. Social Activities and Risk of Dementia in Community-Dwelling Older People: Gender-Specific Findings from a Prospective Cohort Study. J Gerontol Series B. 2024; Apr 3, doi:10.1093/geronb/gbae050.
• Clayton-Chubb D, Kemp WW, Majeed A, Woods RL, Ryan J, Murray AM, Chong TTJ, Lubel JS, Tran C, Hodge AD, Schneider HG, McNeil JJ, Roberts SK. Late-Life Metabolic Dysfunction-Associated Steatotic Liver Disease and its Association With Physical Disability and Dementia. J Gerontol A Biol Sci Med Sci. 2024: Apr 1, doi: 10.1093/gerona/glae011 PMID: 38227760; PMCID: PMC10923210.
• Wang Y, Islam RM, Hussain SM, McNeil JJ, Davis SR. Associations Between Blood Concentrations of Sex Hormones and Physical Function in Community-Dwelling Older Women: A Prospective Cohort Study. J Gerontol A Biol Sci Med Sci. 2024; Apr 17,  doi: 10.1093/gerona/glad287 PMID: 38157294; PMCID: PMC10919882.
• Hussain SM, Seeman E, Schneider HG, Ebeling PR, Barker AL, Polkinghorne K, Newman AB, Yu C, Lacaze P, Owen A, Tran C, Nelson MR, Woods RL, Yeap BB, Clark D, Beilin LJ, McNeil JJ. Association of serum phosphate, calcium and alkaline phosphatase with risk of incident fractures in healthy older adults. J Clin Endocrinol Metab. 2024; Mar 1, doi: 10.1210/clinem/dgae099 [epub ahead of print]. PMID: 38426788.
• Parker EJ, Orchard SG, Gilbert TJ, Phung JJ, Owen AJ, Lockett T, Nelson MR, Reid CM, Tonkin AM, Abhayaratna WP, Gibbs P, McNeil JJ, Woods RL. The ASPREE Healthy Ageing Biobank: Methodology and participant characteristics. PLoS One. 2024; Feb 29, doi: 10.1371/journal.pone.0294743.
• RESEARCH LETTER; Campbell R, Nelson MR, McNeil JJ, McEvoy. Outcomes After Aspirin Discontinuation Among Baseline Users in Contemporary Primary Prevention Aspirin Trials: A Meta-Analysis. Circulation. 2024; Feb 26, doi: 10.1161/CIRCULATIONAHA.123.065420.
• Davis SR, Azene ZN, Tonkin AM, Woods RL, McNeil JJ, Islam RM. Higher testosterone is associated with higher HDL-cholesterol and lower triglyceride concentrations in older women: an observational study. Climacteric. 2024; Feb 12, doi: 10.1080/13697137.2024.2310530.
• Yu C, Bakshi A, Bell RJ, Islam RM, Handelsman DJ, McNeil JJ, Lacaze P, Davis SR. Genome-wide association study identifies genetic regulation of oestrone concentrations and association with endometrial cancer risk in postmenopausal women. eBioMedicine. 2024; Feb 6, doi: 10.1016/j.ebiom.2024.104997.
• Dwyer R, Jachno K, Tran T, Owen A, Layton N, Collyer T, Kirkman M, Lowthian J, Hammarberg K, McNeil JJ, Woods RL, Berk M, Fisher J. Symptoms of depression and risk of emergency department visits among people aged 70 years and over. BMC Public Health. 2024; Feb 5, doi: 10.1186/s12889-024-17794-6.
• Yu C, Robman L, He W, Woods RL, Thao LTP, Wolfe R, Phung J, Makeyeva GA, Hodgson LAB, McNeil JJ, Guymer RH, MacGregor S, Lacaze P. Predictive performance of an updated polygenic risk score for age-related macular degeneration. Ophthalmology. 2024; Jan 31, doi: 10.1016/j.ophtha.2024.01.033 [journal pre-proof].
• RESEARCH LETTER: Yu C, Thanassoulis G, Wolfe R, McNeil JJ, Tonkin AM, Tsimikas S, Lacaze P. Updated lipoprotein(a) genomic risk score and aspirin for primary prevention of cardiovascular events. JACC: Advances. 2024;3(1):100754, doi: 10.1016/j.jacadv.2023.100754.
• Wu Z, Owen A, Woods RL, Cribb L, Alharbi T, Zhou Z, Chong TTJ, Orchard SG, Shah RC, Wolfe R, Torres D, McNeil JJ, Sheets KM, Murray AM, Ryan J. Associations of body habitus and its changes with incident dementia in older adults. J Am Geriatr Soc. 2024; Jan 19, doi: 10.1111/jgs.18757.
• Clayton-Chubb D, Kemp WW, Majeed A, Woods RL, Ryan J, Murray AM, Chong TTJ, Lubel JS, Tran C, Hodge AD, McNeil JJ, Roberts SK. Late-life metabolic dysfunction-associated steatotic liver disease and its association with physical disability and dementia. J Gerontol A. 2024; Jan 06, doi: 10.1093/gerona/glae011.

2023

• Wang Y, Islam RM, Hussain SM, McNeil JJ, Davis SR. Associations between blood concentrations of sex hormones and physical function in community-dwelling older women: a prospective cohort study. The Journals of Gerontology: Series A [accepted manuscript] 2023; Dec 29, doi: 10.1093/gerona/glad287.
• Zoungas S, Zhou Z, Owen AJ, Curtis AJ, Espinoza SE, Ernst ME, Woods RL, Orchard SG, McNeil JJ, Murray AM, Nelson MR, Reid CM, Ryan J, Wolfe R. Daily low-dose aspirin and incident type 2 diabetes in community-dwelling healthy older adults: a post-hoc analysis of efficacy and safety in the ASPREE randomised placebo-controlled trial. The Lancet Diabetes & Endocrinology. 2023; Dec 21, doi: 10.1016/S2213-8587(23)00327-3 [online]. Accompanying editorial.
• Alif SM, Benke GP, Ronaldson KJ, Walker-Bone K, Woods RL, Tran C, Beilin LJ, Tonkin AM, Owen AJ, McNeil JJ. Occupational characteristics and disability-free survival after retirement age: an exploratory analysis from the ASPREE study. Frontiers in Public Health. 2023; Dec 15, doi: 10.3389/fpubh.2023.1191343.
• Hussain SM, Robb C, Tonkin AM, Lacaze P, Chong TT-J, Beilin LJ, Chenglong Y, Watts GF, Ryan J, Ernst M, Zhen Z, Neumann JT, McNeil JJ. Association of plasma high-density lipoprotein cholesterol level with risk of incident dementia: a cohort study of healthy older adults. The Lancet Regional Health – Western Pacific. 2023; Nov 29, doi: 10.1016/j.lanwpc.2023.100963.
• Fravel MA, Ernst ME, Woods RL, Beilin L, Zhou Z, Orchard SG, Chowdhury E, Reid CM, Ekram ARMS, Espinosa SE, Nelson MR, Stocks N, Polkinghorne KR, Wolfe R, Ryan J. Long-term blood pressure variability and frailty risk in older adults. J Hypertension. 2023; Nov 21, doi: 10.1097/HJH.0000000000003599.
• Vishwanath S, Hopper I, Chowdhury EK, Wolfe R, Freak-Poli R, Reid CM, Tonkin AM, Murray AM, Shah RC, Chong TT-J, Woods RL, McNeil JJ, Orchard SG, Nelson MR, Steves CJ, Ryan J. Cardiovascular disease risk scores and incident dementia and cognitive decline in older men and women. Gerontology. 2023; Nov 20, doi: 10.1159/000535284.
• Ball J, Neumann JT, Tonkin AM, Kirchhof P, Freedman B, Brodtmann A, Reid C, Nelson MR, Beilin LJ, Fitzgerald S, Stub D, Woods RL, McNeil JJ. Low-dose aspirin and incident atrial fibrillation in healthy older individuals: a post-hoc analysis of the ASPREE Trial. Eur Heart J Cardiovasc Pharmacother. 2023 Nov 10, doi: 10.1093/ehjcvp/pvad082 [accepted manuscript].
• Alif SM, Benke GP, Kromhout H, Vermeulen R, Tran C, Ronaldson K, Walker-Bone K, Woods RL, Beilin L, Tonkin A, Owen AJ, McNeil JJ. Long-term occupational exposures on disability-free survival and mortality in older adults. Occupational Medicine. 2023; Nov 8, doi: 10.1093/occmed/kqad105.
• Yu C, Bakshi A, Watts GF, Renton AE, Fulton-Howard B, Goate AM, Natarajan P, Chasman DI, Robman L, Woods RL, Guymer R, Wolfe R, Thao LTP, McNeil JJ, Tonkin AM, Nicholls SJ, Lacaze P. Genome-wide association study of cardiovascular resilience identifies protective variation in the CETP gene. JAHA 2023; Nov 7, doi: 10.1161/JAHA.123.031459 [epub ahead of print].
• Khan S, Chen Y, Crocombe L, Ivey E, Owen AJ, McNeil JJ, Woods RL, Wolfe R, Freak-Poli R, Britt C, Gasevic D. Self-reported oral health status, edentulism and all-cause mortality risk in 12 809 Australian older adults: a prospective cohort study. Aust Dent J. 2023; Nov 2, doi: 10.1111/adj.12987 [epub ahead of print].
• Zhou Z, Ryan J, Tonkin AM, Zoungas S, Lacaze P, Wolfe R, Orchard SG, Murray AM, McNeil JJ, Yu C, Watts GF, Hussain SM, Beilin LJ, Ernst M, Stocks N, Woods RL, Zhu C, Reid C, Shah RC, Chong TT, Sood A, Sheets KM, Nelson M. Association Between Triglycerides and Risk of Dementia in Community-Dwelling Older Adults: A Prospective Cohort Study. Neurology. 2023; Oct 25, doi: 10.1212/WNL.0000000000207923.
• Phyo AZZ, Fransquet PD, Wrigglesworth J, Woods RL, Espinoza SE, Ryan J. Sex differences in biological aging and the association with clinical measures in older adults. Geroscience. 2023; Sep 25, doi: 10.1007/s11357-023-00941-z [epub ahead of print].
• Zhou Z, Orchard SG, Nelson MR, Fravel MA, Ernst ME. Angiotensin Receptor Blockers and Cognition: a Scoping Review. Curr Hypertens Rep. 2023; Sept 21, doi: 0.1007/s11906-023-01266-0.
• McGuinness MB, Robman L, Hodgson LAB, Tran C, Woods RL, Owen AJ, McNeil JJ, Makeyeva G, Abhayaratna WP, Guymer RH. Diagnostic accuracy of self-reported age-related macular degeneration in the ASPREE Longitudinal Study of Older Persons. Eye. 2023; Sept 20, doi: 10.1038/s41433-023-02754-y.
• Zhou A, Britt C, Woods RL, Orchard SG, Murray AM, Shah RC, Rajan R, McNeil JJ, Chong TT, Storey E, Ryan J. Normative Data for Single-Letter Controlled Oral Word Association Test in Older White Australians and Americans, African-Americans, and Hispanic/Latinos. J Alzheimers Dis Rep. 2023; Sep 19, doi: 10.3233/ADR-230089 PMID: 37849629; PMCID: PMC10578329.
• Nilaweera D, Gurvich C, Freak-Poli R, Woods RL, Owen A, McNeil J, Nelson M, Stocks N, Ryan J. The association between adverse events in later life and mortality in older individuals. Compr Psychoneuroendocrinol. 2023; Sep 15, doi: 10.1016/j.cpnec.2023.100210 PMID: 37753199, PMCID: PMC10518669.
• Wolfe R, Broder J, Chan A, Murray A, Orchard SG, Polekhina G, Ryan J, Tonkin A, Webb K, Woods RL. Expanded statistical analysis plan for legacy and long-term effects of aspirin in the ASPREE-XT observational follow-up study of participants in the ASPREE randomized trial. medRxiv. 2023; Sept 14, doi: 10.1101/2023.09.13.23295514 [pre-print, has not been peer-reviewed].
• Clayton-Chubb D, Kemp WW, Majeed A, Lubel JS, Woods RL, Tran C, Ryan J, Hodge A, Schneider HG, McNeil JJ, Roberts SK. Metabolic dysfunction‐associated steatotic liver disease in older adults is associated with frailty and social disadvantage. Liver International. 2023; Sept 12, doi: 10.1111/liv.15725.
• Davis SR. Testosterone and the heart: friend or foe? Climacteric. 2023; Sept 4, doi: 10.1080/13697137.2023.2250252.
• Hussain SM, Tonkin AM, Watts GF, Lacaze P, Yu C, Beilin LJ, Zhou Z, Newman AB, Neumann JT, Tran C, McNeil JJ. Sex-dependent associations of plasma high-density lipoprotein cholesterol and mortality risk in healthy older men and women: two prospective cohort studies. Geroscience. 2023; Aug 23, doi: 10.1007/s11357-023-00904-4 [epub ahead of print].
• Smith CL, Kasza J, Woods RL, Lockery JE, Kirpach B, Reid C, Storey E, Nelson MR, Shah RC, Orchard SG, Ernst ME, Tonkin AM, Murray AM, McNeil JJ, Wolfe R. Compliance-adjusted estimates of aspirin effects in older persons in the ASPREE randomized trial, American Journal of Epidemiology. 2023; Aug 8, doi: 10.1093/aje/kwad168 [published manuscript].
• Islam RM, Bell RJ, Berk M, Handelsman DJ, McNeil JJ, Wolfe R, Woods RL, Davis SR. Associations between low sex hormone concentrations and depression in older women: An observational study. Maturitas. 2023; Aug 4, doi: 10.1016/j.maturitas.2023.107822 [journal pre-proof].
• REVIEW: Bhatia HS. Aspirin and lipoprotein(a) in primary prevention. Curr Opin Lipidol. 2023; Oct 1, doi: 10.1097/MOL.0000000000000891 [epub 2023 Jul 31].
• ABSTRACT: Ganjali S, Lotfaliany Abrand Abadi M, Tonkin A, Nelson MR, Reid CM, McNeil JJ, Wolfe R, Chowdhury E, Woods RL, Berk M, Mohebbi M. Validation of Cardiovascular Disease Risk Prediction Models in Community-dwelling Australian and US Older Adults. Heart, Lung and Circulation. 2023; Jul 30, doi: 10.1016/j.hlc.2023.06.560.
• Cloud GC, Williamson JD, Thao LTP, Tran C, Easton CB, Wolfe R, Nelson MR, Reid CM, Newman AB, Lockery J, Fitzgerald SM, Murray AM, Shah RC, Woods RL, Donnan GA, McNeil JJ. Low-Dose Aspirin and the Risk of Stroke and Intracerebral Bleeding in Healthy Older People: Secondary Analysis of a Randomized Clinical Trial. JAMA Netw Open. 2023; Jul 26, doi: 10.1001/jamanetworkopen.2023.25803.
• Wu Z, Pandigama DH, Wrigglesworth J, Owen A, Woods RL, Chong TT, Orchard SG, Shah RC, Sheets KM, McNeil JJ, Murray AM, Ryan J. Lifestyle Enrichment in Later Life and Its Association With Dementia Risk. JAMA Netw Open. 2023; Jul 14, doi: 10.1001/jamanetworkopen.2023.23690.
• Alharbi TA, Owen AJ, Ryan J, Gasevic D, McNeil JJ, Woods RL, Nelson MR, Freak-Poli R. Socio-Demographic, Lifestyle, and Clinical Characteristics of Early and Later Weight Status in Older Adults: Secondary Analysis of the ASPREE Trial and ALSOP Sub-Study. Geriatrics (Basel). 2023; Jun 29, doi: 10.3390/geriatrics8040071 PMID: 37489319; PMCID: PMC10366913.
• McQuilten ZK, Thao LTP, Pasricha SR, Artz AS, Bailey M, Chan AT, Cohen HJ, Lockery JE, Murray AM, Nelson MR, Schneider HG, Wolfe R, Woods RL, Wood EM, McNeil JJ. Effect of Low-Dose Aspirin Versus Placebo on Incidence of Anemia in the Elderly : A Secondary Analysis of the Aspirin in Reducing Events in the Elderly Trial. Ann Intern Med. 2023; Jun 20, doi: 10.7326/M23-0675 [epub ahead of print].
• Mehta R, Kochar B, Zhou Z, Broder JC, Chung P, Yang K, Lockery J, Fravel M, Ryan J, Mahady S, Orchard SG, McNeil JJ, Murray A, Woods RL, Ernst ME, Chan AT. Association of Proton Pump Inhibitor Use with Incident Dementia and Cognitive Decline in Older Adults: A Prospective Cohort Study. Gastroenterology. 2023; Jun 12, doi: 10.1053/j.gastro.2023.05.052.
• Gutteridge D, Segal A, McNeil JJ, Beilin L, Brodtmann A, Chowdhury E, Egan GF, Ernst ME, Hussain M, Reid CM, Robb C, Ryan J, Woods R, Keage H, Jamadar S. The Relationship between Long-Term Blood Pressure Variability and Cortical Thickness in Older Adults.  Neurobiology of Aging. 2023; May 22, doi: 10.1016/j.neurobiolaging.2023.05.011.
• Ernst ME, Broder JC, Wolfe R, Woods RL, Nelson MR, Ryan J, Shah RC, Orchard SG, Chan AT, Espinoza SE, Wilson M, Kirpach B, Reid CM, McNeil JJ, Williamson JD, Murray AM; ASPREE Investigator Group. Health characteristics and aspirin use in participants at the baseline of the aspirin in reducing events in the elderly – eXTension (ASPREE-XT) observational study. Contemp Clin Trials. 2023; May 15, doi: 10.1016/j.cct.2023.107231 [online ahead of print] PMID: 37196887.
• Yu C, Ryan J, Orchard SG, Robb C, Woods RL, Wolfe R, Renton AE, Goate AM, Brodtmann A, Shah RC, Chong TT, Sheets K, Kyndt C, Sood A, Storey E, Murray AM, McNeil JJ, Lacaze P. Validation of newly derived polygenic risk scores for dementia in a prospective study of older individuals. Alzheimers Dement. 2023; May 12, doi: 10.1002/alz.13113 [online ahead of print].
• Zhou Z, Ryan J, Nelson MR, Woods RL, Orchard SG, Zhu C, Gilmartin-Thomas JFM, Fravel MA, Owen AJ, Murray AM, Espinoza SE, Ernst ME. The association of allopurinol with persistent physical disability and frailty in a large community based older cohort. J Am Geriatr Soc. 2023; May 9, doi: 10.1111/jgs.18395 [online ahead of print].
• Pham T, McNeil JJ, Barker AL, Orchard SG, Newman AB, Robb C, Ernst ME, Espinosa S, Woods RL, Nelson MR, Beilin L, Hussain SM. Longitudinal association between handgrip strength, gait speed and risk of serious falls in a community-dwelling older population. PLoS ONE. 2023; May 8, doi: 10.1371/journal.pone.0285530.
• Wang Y, Owen A, Franks A, Ackerman I, Fitzgerald SM, Liew S, Woods RL, Wluka AE, McNeil JJ, Cicuttini FM. Functional outcomes following knee replacement in community-dwelling older adults. BMC Geriatr. 2023; May 2, doi: 10.1186/s12877-023-03925-y.
• McGuinness MB, Robman LD, McNeil JJ, Tran C, Woods RL, Owen AJ, Pham T, Guymer RH. Self-rated eyesight among healthy older Australians: Baseline results of the ASPREE Longitudinal Study of Older Persons. Clin Exp Ophthalmol. 2023; Apr 28, doi: 10.1111/ceo.14233 [epub ahead of print]. PMID: 37114419.
• Nilaweera D, Gurvich C, Freak-Poli R, Woods R, Owen A, Murray A, Orchard SG, Britt C, Wu Z, McNeil J, Ryan J. Adverse events in older adults and the risk of dementia and cognitive decline. J Affect Disord Rep. 2023; Apr 28, doi: 10.1016/j.jadr.2023.100592 [epub] PMID: 37475782; PMCID: PMC10357969.
• Zhou Z, Curtis AJ, Owen A, Wolfe R, Murray AM, Tonkin AM, Ernst ME, Orchard SG, Zhu C, Carr PR, Reid CM, Espinoza SE, Shah RC, Woods RL, Ryan J, McNeil JJ, Nelson MR, Zoungas S. Prediabetes, diabetes and loss of disability-free survival in a community-based older cohort: a post-hoc analysis of the ASPirin in Reducing Events in the Elderly trial. Age Ageing. 2023; Apr 23, doi: 10.1093/ageing/afad060. PMID: 37097768. PMCID: PMC10128162
• Alharbi TA, Ryan J, Freak-Poli R, Gasevic D, McNeil JJ, Woods RL, Britt C, Nelson MR, Owen AJ. Self-Reported Early and Later Life Weight and the Risk of All-Cause Mortality in Older Adults. J Nutr Health Aging. 2023; Apr 14, doi: 10.1007/s12603-023-1907-1.
• Hussain SM, Newman AB, Beilin LJ, Tonkin AM, Woods RL, Neumann JT, Nelson M, Carr PR, Reid CM, Owen AJ, Ball J, Cicuttini FM, Tran C, Wang Y, Ernst ME, McNeil JJ. Associations of change in body size with all-cause and cause-specific mortality among healthy older adults. JAMA Network Open 2023; Apr 10, doi: 10.1001/jamanetworkopen.2023.7482.
• Lockery JE, Collyer TA, Woods RL, Orchard SG, Murray A, Nelson MR, Stocks NP, Wolfe R, Moran C, Ernst ME; ASPREE Investigator Group. Potentially inappropriate medication use is associated with increased risk of incident disability in healthy older adults. J Am Geriatr Soc. 2023; Apr 11, doi: 10.1111/jgs.18353 [epub ahead of print]. PMID: 37039393
• Bakshi A, Jefferis J, Wolfe R, Wetmore JB, McNeil JJ, Murray AM, Polkinghorne KR, Mallett A, Lacaze P. Association of polygenic scores with chronic kidney disease phenotypes in a longitudinal study of older adults. Kidney Int. 2023, doi: 10.1016/j.kint.2023.03.017 [epub ahead of print 2023; Mar 29]. PMID: 37001602
• Teshale AB, Htun HL, Hu J, Dalli LL, Lim MH, Barbara Barbosa Neves B, Baker JR, Phyo AZZ, Reid CM, Joanne Ryan J, Owen AJ, Fitzgerald SM, Freak-Poli R. The relationship between social isolation, social support, and loneliness with cardiovascular disease and shared risk factors: A narrative review. Archives of Gerontology and Geriatrics. 2023; Mar 23, doi: 10.1016/j.archger.2023.105008.
• Robb C, Carr P, Ball J, Owen A, Beilin LJ, Newman AB, Nelson MR, Reid CM, Orchard SG, Neumann JT, Tonkin AM, Wolfe R, McNeil JJ. Association of a Healthy Lifestyle with Mortality in Older People. Res Sq . 2023, doi: 10.21203/rs.3.rs-2541145/v1 [preprint, 2023; Mar 13] PMID: 36993471. PMCID: PMC10055537
• Saifuddin Ekram ARM, Tonkin AM, Ryan J, Beilin L, Ernst ME, Espinoza SE, JMcNeil JJ, Nelson MR, Reid CM, Newman AB, Woods RL. The association between frailty and incident cardiovascular disease events in community-dwelling healthy older adults. American Heart Journal Plus: Cardiology Research and Practice. 2023, doi: 10.1016/j.ahjo.2023.100289 [pre-proof online 2023; Mar 8].
• Carr PR, Webb KL, Neumann JT, Thao LTP, Beilin LJ, Ernst ME, Fitzgibbon B, Gasevic D, Nelson MR, Newman AB, Orchard SG, Owen A, Reid CM, Stocks NP, Tonkin AM, Woods RL, McNeil JJ. Associations of body size with all-cause and cause-specific mortality in healthy older adults. Sci Rep. 2023; Mar 7, doi: 10.1038/s41598-023-29586-w.
• Orchard SG, Lockery JE, Broder JC, Ernst ME, Espinoza S, Gibbs P, Wolfe R, Polekhina G, Zoungas S, Loomans-Kropp HA, Woods RL. Association between metformin, aspirin and cancer incidence and mortality risk in adults with diabetes. JNCI Cancer Spectr. 2023, doi: 10.1093/jncics/pkad017 [online ahead of print 2023; Mar 1]. PMID: 36857596
• Vishwanath S, Hopper I, Wolfe R, Polekhina G, Reid CM, Tonkin AM, Murray AM, Shah RC, Storey E, Woods RL, McNeil J, Orchard SG, Nelson MR, Steves CJ, Ryan J. Cognitive trajectories and incident dementia after a cardiovascular event in older adults. Alzheimer’s Dementia. 2023; Mar 1, doi: 10.1002/alz.13006.
• Fravel MA, Ernst ME, Gilmartin-Thomas J, Woods RL, Orchard SG, Owen AJ; ASPirin in Reducing Events in the Elderly Investigator Group. Dietary supplement and complementary and alternative medicine use among older adults in Australia and the United States. J Am Geriatr Soc. 2023, doi: 10.1111/jgs.18305 [epub ahead of print 2023; Feb 28]. PMID: 36852896
• Wrigglesworth J, Harding IH, Islam RM, Ward PGD, Woods RL, Bell RJ, McNeil JJ, Storey E, Egan G, Murray AM, Trevaks RE, Ward SA, Davis SR, Ryan J. The association between sex hormones and the change in brain-predicted age difference in older women. Clinical Endocrinology. Accepted Author Manuscript, 2023; Feb 20, doi: 10.1111/cen.14898.
• Al-Kaisey A, Wong GR, Young P, Chieng D, Hawson J, Anderson R, Sugumar H, Nalliah C, Prabhu M, Johnson R, Soka M, Tarr I, Bakshi A, Yu C, Lacaze P, Giannoulatou E, McLellan A, Lee G, Kistler PM, Fatkin D, Kalman JM. Polygenic Risk Scores are Associated with Atrial Electrophysiologic Substrate Abnormalities and Outcomes Following Atrial Fibrillation Catheter Ablation. Heart Rhythm. 2023; Feb 16, doi: 10.1016/j.hrthm.2023.02.011.
• Wu Z, Woods RL, Chong TT-J, et al. Grip strength, gait speed, and trajectories of cognitive function in community-dwelling older adults: A prospective study. Alzheimer’s Dement. 2023; Feb 14, doi: 10.1002/dad2.12388.
• Craig H, Gasevic D, Ryan J, Owen A, McNeil J, Woods R, Britt C, Ward S, Freak-Poli R. Socioeconomic, Behavioural, and Social Health Correlates of Optimism and Pessimism in Older Men and Women: A Cross-Sectional Study. International Journal of Environmental Research and Public Health. 2023; Feb 13, doi: 10.3390/ijerph20043259.
• Muhandiramge J, Warner ET, Zalcberg JR, Haydon A, Polekhina G, van Londen GJ, Gibbs P, Bernstein WB, Tie J, Millar JL, Mar VJ, McNeil JJ, Woods RL, Orchard SG, on behalf of the ASPREE Investigator Group. Cancer Treatment Patterns and Factors Affecting Receipt of Treatment in Older Adults: Results from the ASPREE Cancer Treatment Substudy (ACTS). Cancers. 2023; Feb 5, doi: 10.3390/cancers15041017.
• Wild H, Gasevic D, Woods RL, Ryan J, Berk M, Wolfe R, McNeil J, Owen AJ. Correlates of Meal Skipping in Community Dwelling Older Adults: A Cross-Sectional Study. J Nutr Health Aging. 2023; Feb 3, doi: 10.1007/s12603-023-1884-2.
• Sultana F, Davis SR, Murray AM, Woods RL, McNeil JJ, Islam RM. Sex hormones, SHBG and cognitive performance among older Australian women: an observational study. Climacteric. 2023; Jan 30, doi: 10.1080/13697137.2023.2166824 [epub ahead of print]. PMID: 36716780
• Azene ZN, Davis SR, McNeil JJ, Tonkin AM, Handelsman DJ, Islam RM. Estrone, sex hormone binding globulin and lipid profiles in older women: an observational study. Climacteric. 2023, doi: 10.1080/13697137.2023.2165908 [online 2023; Jan 24].
• Mahady SE, Polekhina G, Woods RL, Margolis KL, Wetmore JB, Wood EM, Cloud GC, Murray AM, Wolfe R, Polkinghorne KR. Association between chronic kidney disease and major hemorrhage in older persons: data from the ASPREE randomized trial. Kidney International Reports. 2023, doi: 10.1016/j.ekir.2023.01.012 [pre-proof online 2023; Jan 19].
• Hussain SM, Ebeling PR, Barker AL, Beilin LJ, Tonkin AM, McNeil JJ. Association of Plasma High-Density Lipoprotein Cholesterol Level With Risk of Fractures in Healthy Older Adults. JAMA Cardiol. 2023, doi:10.1001/jamacardio.2022.5124 [online 2023; Jan 18].
• Ekram ARMS, Ryan J, Espinoza S, Newman AB, Murray AM, Orchard SG, Fitzgerald S, McNeil JJ, Ernst ME, Woods RL. The association between frailty and dementia-free and physical disability-free survival in community-dwelling older adults. Gerontology 2023, doi: 10.1159/000528984 [online 2023; Jan 7].
• Wrigglesworth J, Ryan J, Ward PGD, Woods RL, Storey E, Egan GF, Murray A, Espinoza SE, Shah RC, Trevaks RE, Ward SA, Harding IH. Health-related heterogeneity in brain aging and associations with longitudinal change in cognitive function. Frontiers in Aging Neuroscience. 2023, doi: 10.3389/fnagi.2022.1063721 [online 2023; Jan 4].

2022

• Fravel MA, Ernst ME, Webb KL, Wetmore JB, Wolfe R, Woods RL, Reid CM, Chowdhury E, Murray AM, Polkinghorne KR, ASPirin in Reducing Events in the Elderly Investigator Group. GFR Variability, Survival, and Cardiovascular Events in Older Adults. Kidney Medicine. 2022, doi: 10.1016/j.xkme.2022.100583 [pre proof online 2022; Dec 12].  Accompanying editorial doi: 10.1016/j.xkme.2023.100599
• LETTER: Phyo AZZ, Ryan J, Freak-Poli R. The role of health-related quality of life in risk prediction for developing cardiovascular disease, dementia and all-cause death among general older adults. Frontiers in Public Health. 2022; Nov 17, doi: 10.3389/fpubh.2022.1014019.
• ABSTRACT: McQuilten Z, Wong NC, Leichter A, Thao LTP, Phung J, Murphy AJ, Riaz M, Sebra R, Bick AG, McNeil JJ, Wolfe R, Woods RL, Lacaze P, Wood EM, Curtis DJ. The Effect of Clonal Hematopoiesis of Indeterminate Potential (CHIP) and Aspirin on Clinical Outcomes in the Healthy Elderly: A Sub-Study of the Aspirin in Reducing Events in the Elderly (ASPREE) Randomized Controlled Trial. Blood. 2022; Nov 15, doi: 10.1182/blood-2022-170761.
• ABSTRACT: Curtis DJ, Wong NC,  Leichter A, Thao LTP, Phung J, Murphy AJ, Riaz M, Sebra R, Bick AG, McNeil JJ, Wolfe R, Woods RL, Lacaze P, Wood EM, McQuilten Z. The Growth Kinetics of Clonal Hematopoiesis Inform Risk of Blood Cancer Progression. Blood. 2022; Nov 15, doi: 10.1182/blood-2022-168526.
• Saifuddin Ekram ARM, Espinosa SE, Ernst ME, Ryan J, Beilin L, Stocks NP, Ward SA, McNeil JJ, Shah RC, Woods RL. Association between metabolic syndrome, frailty and disability-free survival in healthy community-dwelling older adults. J Nutr Health Aging. 2022; Nov 14, doi: 10.1007/s12603-022-1860-2.
• Barker AL, Morello R, Thao LTP, Seeman E, Ward SA, Sanders KM, Cumming RG, Pasco JA, Ebeling PR, Woods RL, Wolfe R, Khosla S, Hussain SM,  Ronaldson K, Newman AB, Williamson JD, McNeil JJ. Daily Low-Dose Aspirin and Risk of Serious Falls and Fractures in Healthy Older People: A Substudy of the ASPREE Randomized Clinical Trial. JAMA Intern Med. 2022, doi:10.1001/jamainternmed.2022.5028 [online 2022; Nov 7].
• Roebuck G, Lotfaliany M, Agustini B, Forbes M, Mohebbi M, McNeil J, Woods RL, Reid CM, Nelson MR, Shah RC, Ryan J, Newman AB, Owen A, Freak-Poli R, Stocks N, Berk M; ASPREE Investigator Group. The effect of depressive symptoms on disability-free survival in healthy older adults: a prospective cohort study. Acta Psychiatr Scand. 2022; Oct 25, doi: 10.1111/acps.13513 [epub ahead of print]. PMID: 36281968
• Walker RG, Wolfe R, Bongetti E, Polkinghorne KR, Woods RL, Ryan J, Espinoza S, Murray A, Ernst ME, McNeil JJ, ASPREE Investigator Group. The association of Frailty with Chronic Kidney Disease in Older Adults using the ASPirin in Reducing Events in the Elderly Cohort. Nephrology. 2022, doi: 10.1111/nep.14123 [online 2022; Oct 17].
• Jackno KM, Heritier S, Woods RL, Mahady S, Chan A, Tonkin A, Murray A, McNeil JJ, Wolf R. Examining evidence of time-dependent treatment effects: an illustration using regression methods. Trials. 2022, doi:10.1186/s13063-022-06803-x [online 2022; Oct 11].
• Lacaze P, Bakshi A, Riaz M, Polekhina G, Owen A, Bhatia HS, Natarajan P, Wolfe R, Beilin L, Nicholls SJ, Watts GF, McNeil JJ, Tonkin AM, Tsimikas S. Aspirin for Primary Prevention of Cardiovascular Events in Relation to Lipoprotein(a) Genotypes. J Am Coll Cardiol. 2022; Oct 4, doi: 10.1016/j.jacc.2022.07.027. PMID: 36175048.
• Mishra A, Malik R, Hachiya T, Jürgenson T, Namba S, Posner DC, Kamanu FK, Koido M, Le Grand Q, Shi M, He Y, Georgakis MK, Caro I, Krebs K, Liaw YC, Vaura FC, Lin K, Winsvold BS, Srinivasasainagendra V, Parodi L, Bae HJ, Chauhan G, Chong MR, Tomppo L, Akinyemi R, Roshchupkin GV, Habib N, Jee YH, Thomassen JQ, Abedi V, Cárcel-Márquez J, Nygaard M, Leonard HL, Yang C, Yonova-Doing E, Knol MJ, Lewis AJ, Judy RL, Ago T, Amouyel P, Armstrong ND, Bakker MK, Bartz TM, Bennett DA, Bis JC, Bordes C, Børte S, Cain A, Ridker PM, Cho K, Chen Z, Cruchaga C, Cole JW, de Jager PL, de Cid R, Endres M, Ferreira LE, Geerlings MI, Gasca NC, Gudnason V, Hata J, He J, Heath AK, Ho YL, Havulinna AS, Hopewell JC, Hyacinth HI, Inouye M, Jacob MA, Jeon CE, Jern C, Kamouchi M, Keene KL, Kitazono T, Kittner SJ, Konuma T, Kumar A, Lacaze P et al. Stroke genetics informs drug discovery and risk prediction across ancestries. Nature. 2022; Sep 30, doi: 10.1038/s41586-022-05165-3 [epub 2022; Sep 30. Erratum in: Nature. 2022; Nov 14].
• Orchard SG, Polekhina G, Ryan J, Shah RC, Storey E, Chong TTJ, Lockery JE, Ward SA, Wolfe R, Nelson MR, Reid CM, Murray AM, Espinoza SE, Newman AB, McNeil JJ, Collyer TA, Callisaya ML, Woods RL, on behalf of the ASPREE Investigator Group. Combination of gait speed and grip strength to predict cognitive decline and dementia. Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, 2022, doi: 10.1002/dad2.12353 [online 2022; Sep 13].
• Tse AWW, Ward S, McNeil JJ, Barker A, Cicuttini F, Fitzgibbon BM, Hussain SM, Owen A, Wang Y, Wolfe R, Gilmartin-Thomas JF. Severe low back or lower limb pain is associated with recurrent falls among older Australians. Eur J Pain. 2022; Sep 1, doi: 10.1002/ejp.2013, [epub 2022 Sep 1.] PMID: 35862463.
• Wang Y, Owen A, Franks A, Ackerman I, Fitzgerald SM, Liew S, Woods RL, Wluka AE, McNeil JJ, Cicuttini F. Functional outcomes following hip replacement in community-dwelling older adults. J Clin Med. 2022; Aug 30, doi: 10.3390/jcm11175117.
• Liew SM, Chowdhury EK, Ernst ME, Gilmartin-Thomas J, Reid CM, Tonkin A, Neumann J, McNeil JJ, Kaye DM. Prescribed opioid use is associated with adverse cardiovascular outcomes in community-dwelling older persons. ESC Heart Failure. 2022, doi: 10.1002/ehf2.14101 [online 2022; Aug 19].
• Wu Z, Woods RL, Chong TTJ, Orchard SG, McNeil JJ, Shah RC, Wolfe R, Murray AM, Storey E, Ryan J. Potential modifiable factors associated with late-life cognitive trajectories. Frontiers in Neurology. 2022, doi: 10.3389/fneur.2022.950644 [online 2022; Aug 3].
• Zaman FY, Orchard SG, Haydon A, Zalcberg JR. Non-aspirin non-steroidal anti-inflammatory drugs in colorectal cancer: a review of clinical studies. Br J Cancer. 2022; June 28, doi: 10.1038/s41416-022-01882-8.
• Wu Z, Woods RL, Chong TTJ, Orchard SG, Shah RC, Wolfe R, Storey E, Sheets KM, Murray AM, McNeil JJ, Ryan J. Cognitive trajectories in community-dwelling older adults and incident dementia, disability and death: a 10-year longitudinal study. Frontiers in Medicine. 2022; June 27, doi: 10.3389/fmed.2022.917254.
• Hussain SM, Ernst ME, Barker AL, Margolis KL, Reid CM, Neumann JT, Tonkin AM, Phuong TLT, Beilin LJ, Pham T, Chowdhury EK, Cicuttini FM, Gilmartin-Thomas JFM, Carr PR, McNeil JJ. Variation in Mean Arterial Pressure increases Falls Risk in Elderly Physically Frail and Pre-frail Individuals Treated with Antihypertensive Medication. Hypertension. 2022; June 20, doi: 10.1161/HYPERTENSIONAHA.122.19356.
• Webb K, Ryan J, Wolfe R, Woods RL, Shah RC, Murray AM, Orchard SG, Storey E. Test-Retest Reliability and Minimal Detectable Change of Four Cognitive Tests in Community-Dwelling Older Adults. Journal of Alzheimer’s Disease. 2022: June 14, doi: 10.3233/JAD-215564.
• Collyer TA, Murray AM, Woods RL, Storey E, Chong TJ, Ruan J, Orcahrd SG, Brdotmann A, Srikanth VK, Shah RC, Callisaya ML. Association of Dual Decline in Cognition and Gait Speed With Risk of Dementia in Older Adults. JAMA Netw Open. 2022; May 31, doi:10.1001/jamanetworkopen.2022.14647. Accompanying EDITORIAL 2022; May 31, doi: 10.1001/jamanetworkopen.2022.14654.
• Downie JM, Riaz M, Xie J, Lee M, Chan AT, Gibbs P, Orchard SG, Mahady SE, Sebra RP, Murray AM, Macrae F, Schadt E, Woods RL, McNeil JJ, Lacaze P, Gala M. Incident Cancer Risk and Signatures Among Older MUTYH Carriers: Analysis of Population-Based and Genomic Cohorts. Cancer Prev Res (Phila). 2022; May 31, doi: 10.1158/1940-6207.CAPR-22-0080.
• Hu Y, Carr PR, Liew D, Broder J, Callander EJ, McNeil JJ. How does the onset of physical disability or dementia in older adults affect economic wellbeing and co-payments for health care? The impact of gender. BMC Health Serv Res. 2022; May 25, doi: 10.1186/s12913-022-08017-y.
• Ward SA, Storey E, Gasevic D, Naughton MT, Hamilton GS, Trevaks RE, Wolfe R, O’Donoghue F, Stocks N, Abhayaratna WP, Fitzgerald S, Orchard SG, Ryan J, McNeil JJ, Reid CM, Woods RL. Sleep-disordered breathing was associated with lower health-related quality of life and cognitive function in a cross-sectional study of older adults. Respirology. 2022; May 17, doi.org/10.1111/resp.14279.
• Yan MK, Orchard SG, Adler NR, Wolfe R, McLean C, Rodríguez LM, Woods RL, Gibbs P, Chan AT, Haydon A, Mar VJ. Association between hypertension and cutaneous melanoma, and the effect of aspirin: extended follow-up of a large randomised controlled trial. Cancer Epidemiol. 2022, doi: 10.1016/j.canep.2022.102173 [online 2022; May 11].
• Lacaze P, Wang Y, Polekhina G, Bakshi A, Riaz M, Owen A, Franks A, Abidi J, Tiller J, McNeil J, Cicuttini F. Genomic risk score for advanced osteoarthritis in older adults. Arthritis Rheumatol. 2022; May 4, doi: 10.1002/art.42156 [online ahead of print].
• Agustini B, Lotfaliany M, Mohebbi M, Woods RL, McNeil JJ, Nelson MR, Shah R, Murray A, Reid CM, Tonkin A, Ryan J, Williams LJ, Forbes MP, Berk M. Trajectories of depressive symptoms in older adults and associated health outcomes. Nat Aging. 2022; Apr 19, doi.org/10.1038/s43587-022-00203-1.
• Jadhao S, Davison C, Roulis EV, Lee S, Lacaze P, Riaz M, McNeil JJ, Thomas DM, Pecheniuk NM, Hyland CA, Flower R, Nagaraj SH. Using Whole Genome Sequencing to Characterize Clinically Significant Blood Groups Among Healthy Older Australians. Blood Adv. 2022; Apr 14, doi: 10.1182/bloodadvances.2022007505.
• Polkinghorne KR, Wetmore JB, Thao LTP, Wolfe R, Woods RL, Ernst ME, Nelson MR, Reid CM, Shah RC, McNeil JJ, Murray AM. Effect of Aspirin on CKD Progression in Older Adults: Secondary Analysis From the ASPREE Randomized Clinical Trial. American Journal of Kidney Diseases. 2022; Apr 14, doi: 10.1053/j.ajkd.2022.02.019 [pre-proof].
• Neumann JT, Thao LTP, Murray AM, Callander E, Carr PR, Nelson MR, Wolfe R, Woods RL, Reid CM, Shah RC, Newman AB, Williamson JD, Tonkin AM, McNeil JJ. Prediction of disability-free survival in healthy older people. GeroScience. 2022; Apr 14, doi.org/10.1007/s11357-022-00547-x.
• Craig H, Ryan J, Freak-Poli R, Owen A, McNeil J, Woods RL, Britt C, Tonkin A, Gasevic D. The Association of Dispositional Optimism and Pessimism With Cardiovascular Disease Events in Older Adults: A Prospective Cohort Study. J Aging Health. 2022, doi: 10.1177/08982643221083118 [online ahead of print, 2022; Apr 11].
• Yan MK, Orchard SG, Adler NR, Wolfe R, McLean C, Rodriguez LM, Woods RL, Gibbs P, Chan AT, Haydon A, Mar VJ. Effect of Aspirin on Melanoma Incidence in Older Persons: Extended Follow-up of a Large Randomized Double-blind Placebo-controlled Trial. Cancer Prev Res (Phila). 2022; Apr 8, doi: 10.1158/1940-6207.CAPR-21-0244 [epub ahead of print]. PMID: 35395069
• Zhou Z, Nelson M, Ernst ME, Reid C, McNeil J, Tonkin A, on behalf of the ASPREE Investigator Group. Does aspirin prevent incident heart failure in healthy older adults? Examining the evidence from the ASPREE trial. Circulation: Heart Failure 2022; Apr 5, doi: 510.1161/CIRCHEARTFAILURE.122.009511.
• Wrigglesworth J, Harding I, Ward P, Woods RL, Storey E, Fitzgibbon B, Egan G, Murray A, Shah R, Trevaks R, Ward S, McNeil JJ, Ryan J. Factors Influencing Change in Brain-Predicted Age Difference in a Cohort of Healthy Older Individuals. Journal of Alzheimer’s Disease Reports. 2022; April 4, doi:10.3233/ADR-220011.
• ABSTRACT: Bellenguez C, …Lacaze P,…Riaz M, …Lambert JC. New insights into the genetic etiology of Alzheimer’s disease and related dementias. Nat Genet. 2022; Apr 4, doi: 10.1038/s41588-022-01024-z [epub 2022; Apr 4] PMID: 35379992; PMCID: PMC9005347. (>100 coauthors).
• Bakshi A, Cao Y, Orchard SG, Carr PR, Joshi AD, Manning AK, Buchanan DD, Umar A, Winship IM, Gibbs P, Zalcberg JR, Macrae F, McNeil JJ, Lacaze P, Chan A.  Aspirin and the risk of colorectal cancer according to genetic susceptibility among older individuals. Cancer Prev Res (Phila). 2022; Mar 29, doi: 10.1158/1940-6207.CAPR-22-0011 [epub ahead of print].
• Ekram ARMS, Woods RL, Ryan J, Espinoza SE, Gilmartin-Thomas JFM, Shah RC, Mehta R, Kochar B, Lowthian JA, Lockery J, Orchard S, Nelson M, Fravel MA, Liew D, Ernst ME. The association between polypharmacy, frailty and disability-free survival in community-dwelling healthy older individuals. Archives of Gerontology and Geriatrics. 2022; Mar 23, doi: 10.1016/j.archger.2022.104694  [epub ahead of print].
• Phyo AZZ, Gonzalez-Chica DA, Stocks NP, Woods RL, Tran T, Reid CM, Tonkin AT, Nelson MR, McNeil JJ, Murray AM, Gasevic D, Freak-Poli R, Ryan J. Trajectories of physical health-related quality of life and the risk of incident cardiovascular disease events and all-cause mortality in older people. American Heart Journal Plus: Cardiology Research and Practice. 2022, doi: 10.1016/j.ahjo.2022.100117 [published online 2022; Mar 23].
• Nelson MR, Polekhina G, Woods RL, Reid CR, Tonkin AM, Wolfe R, Murray AM, Kirpach B, Ernst ME, Lockery JE, Shah RC, Stocks N, Orchard SG, Zhou Z. Safety of Ceasing Aspirin Used Without a Clinical Indication After Age 70 Years: A Subgroup Analysis of the ASPREE Randomized Trial. Ann Intern Med. 2022; Mar 15, doi: 10.7326/M21-3823 [epub ahead of print]. Accompanying editorial, doi: 10.7326/M22-0550.
• Robb C, Carr P, Ball J, Owen A, Beilin LJ, Newman AB, Nelson MR, Reid CM, Orchard SG, Neumann JT, Tonkin AM, Wolfe R, McNeil JJ. Association of a Healthy Lifestyle with Mortality in Older People. Res Sq . 2023, doi: 10.21203/rs.3.rs-2541145/v1 [preprint, 2023; Mar 13] PMID: 36993471. PMCID: PMC10055537.
• Muhandiramge J, Orchard SG, Warner ET, van Londen GJ, Zalcberg JR. Functional Decline in the Cancer Patient: A Review. Cancers. 2022; Mar 8, doi.org/10.3390/cancers14061368.
• Aschmann HE, McNeil JJ, Puhan MA. Large-scale prevention trials could provide stronger evidence for decision-makers: Opportunities to design and report with a focus on the benefit–harm balance. Clinical Trials. 2022; Feb, 13, (online), doi:10.1177/17407745211068549.
• Islam RM, Bell RJ, Handelsman DJ, McNeil JJ, Nelson MR, Reid CM, Tonkin AM, Wolfe RS, Woods RL, Davis SR. Associations between blood sex steroid concentrations and risk of major adverse cardiovascular events in healthy older women in Australia: a prospective cohort substudy of the ASPREE trial. Lancet Healthy Longev. 2022; Feb 1, doi:10.1016/S2666-7568(22)00001-0. Accompanying editorial, doi.org/10.1016/S2666-7568(22)00008-3.
• Neumann JT, Thao LTP, Callander E, Carr PR, Qaderi V, Nelson MR, Reid CR, Woods RJ. Orchard SG, Wolfe R, Polekhina G, Williamson JMR, Trauer JM, Newman AB, Murray AM, Ernst ME, Tonkin AM, McNeil JJ. A multistate model of health transitions in older people: a secondary analysis of ASPREE clinical trial data. Lancet Healthy Longev. 2022; Feb 1, doi:10.1016/S2666-7568(21)00308-1. Accompanying editorial, doi.org/10.1016/S2666-7568(22)00011-3.
• Govindaraju T, McCaffrey TA, McNeil JJ, Reid CM, Smith BJ, Campbell DJ, Liew D, Owen AJ. Quality of life and associations with health-related behaviours among older adults with increased cardiovascular risk. Nutrition, Metabolism and Cardiovascular Diseases. 2022; Jan 29, doi: 10.1016/j.numecd.2022.01.025 [epub ahead of print].

2021

• Neumann JT, Riaz M, Bakshi A, Polekhina G, Thao LTP, Nelson MR, Woods RL, Abraham G, Inouye M, Reid CM, Tonkin AM, McNeil J, Lacaze P. Prognostic Value of a Polygenic Risk Score for Coronary Heart Disease in Individuals Aged 70 Years and Older. Circ Genom Precis Med. 2021; Dec 24, doi: 10.1161/CIRCGEN.121.003429 [epub ahead of print].
• Freak-Poli R, Ryan J, Neumann JT, Tonkin A, Reid CM, Woods RL, Nelson M, Stocks N,  Berk M, McNeil J, Britt C, Owen A. Social isolation, social support and loneliness as predictors of cardiovascular disease incidence and mortality. BMC Geriatr. 2021; Dec. 13, doi.org/10.1186/s12877-021-02602-2.
• Riaz M, Mattisson J, Polekhina G, Bakshi A, Halvardson J, Danielsson M, Ameur A, McNeil, J, Forsberg LA, Lacaze P.  A polygenic risk score predicts mosaic loss of chromosome Y in circulating blood cells. Cell Biosci. 2021; Dec. 12, doi.org/10.1186/s13578-021-00716-z.
• Southey MC, Dowty JG, Riaz M, Steen JA, Renault AL, Tucker K, Kirk J, James P, Winship I, Pachter N, Poplawski N, Grist S, Park DJ, Pope BJ, Mahmood K, Hammet F, Mahmoodi M, Tsimiklis H, Theys D, Rewse A, Willis A, Morrow A, Speechly C, Harris R, Sebra R, Schadt E, Lacaze P, McNeil JJ, Giles GG, Milne RL, Hopper JL, Nguyen-Dumont T. Population-based estimates of breast cancer risk for carriers of pathogenic variants identified by gene-panel testing. NPJ Breast Cancer. 2021; Dec 9, doi: 10.1038/s41523-021-00360-3.
• Murray AM, Thao LTP, Ryan J, Wolfe R, Wetmore JB, Woods RL, Polkinghorne KR. Chronic kidney disease biomarkers, cognitive impairment and incident dementia in an older healthy cohort. Kidney360. 2021; Dec. 7. doi.org/10.34067/KID.0005672021. Epub ahead of print.
• Broder, JC, Ryan, J, Shah, RC, Lockery JE, Orchard SG, Gilmartin-Thomas JFM, Fravel MA, Owen AJ, Woods RL, Wolfe R, Storey E, Murray AM, Ernst ME. Anticholinergic medication burden and cognitive function in participants of the ASPREE study. Pharmacotherapy. 2021; Dec. 6, doi:10.1002/phar.2652.
• Selvadurai MV, Riaz M, Xie S, Tonkin A, McNeil JJ, Lacaze P, Hamilton J. The PAR4 platelet thrombin receptor variant rs773902 does not impact the incidence of thrombotic or bleeding events in a healthy older population. Thromb Haemost. 2021 Dec 1, doi: 10.1055/a-1711-1395 [epub ahead of print]. PMID: 34852379
• Bakshi A, Riaz M, Orchard SG, Carr PR, Joshi AD, Cao Y, Rebello R, Nguyen-Dumont T, Southey MC, Millar JL, Gately L, Gibbs P, Ford LG, Parnes HL, Chan AT, McNeil JJ, Lacaze P. A Polygenic Risk Score Predicts Incident Prostate Cancer Risk in Older Men but Does Not Select for Clinically Significant Disease. Cancers. 2021; Nov 19, doi: 10.3390/cancers13225815.
• Neumann JT, Thao LTP, Callander E, Chowdhury E, Williamson JD, Nelson MR, Donnan G, Woods RL, Reid CR, Poppe KK, Jackson R, Tonkin AM, McNeil JJ. Cardiovascular risk prediction in healthy older people. GeroScience. 2021; Nov 11, doi: 10.1007/s11357-021-00486-z.
• Espinoza SE, Woods RL, Ekram ARMS, Ernst ME, Polekhina G, Wolfe R, Shah RC, Ward SA, Storey E, Nelson MR, Reid CM, Lockery JE, Orchard SG, Trevaks R, Fitzgerald SM, Stocks NP, Chan A, McNeil JJ, Murray AM, Newman AB, Ryan J; ASPREE Investigator Group. The effect of low-dose aspirin on frailty phenotype and frailty index in community-dwelling older adults in the ASPirin in Reducing Events in the Elderly study. J Gerontol A Biol Sci Med Sci. 2021; Nov 10:glab340, doi: 10.1093/gerona/glab340 [epub ahead of print]. PMID: 34758073
• Joyce J, Ryan J, Owen A, Hu J, McHugh Power J, Shah R, Woods RL, Storey E, Britt C, Freak-Poli R, ASPREE Investigator Groupl. Social isolation, social support, and loneliness and their relationship with cognitive health and dementia. Int J Geriatr Psychiatry. 2021; Nov 5, doi: 10.1002/gps.5644.
• Neumann JT, Freak-Poli R, Orchard SG, Wolfe R, Reid CM, Tonkin AM, Beilin LJ, McNeil JJ, Ryan J, Woods RL. Alcohol consumption and risks of cardiovascular disease and all-cause mortality in healthy older adults. European Journal of Preventive Cardiology. 2021; Oct 28, doi: 10.1093/eurjpc/zwab177.
• Phyo AZZ, Gonzalez-Chica DA, Stocks N,  Woods RLW, Fisher J, Tran T, Owen A, Ward S, Britt C, Ryan J, Freak-Poli R. Impact of economic factors, social health and stressful life events on physical health-related quality of life trajectories in older Australians. Qual Life Res. 2021; Oct 22, doi: 10.1007/s11136-021-03021-x.
• Wrigglesworth J, Yaacob N, Ward P, Woods RL, McNeil JJ, Storey E, Egan G, Murray A, Shah RC, Jamadar SD, Trevaks T, Ward W, Harding IH, Ryan J. Brain-predicted age difference is associated with cognitive processing in later-life. Neurobiology of Aging. 2021; Oct 20, doi: 10.1016/j.neurobiolaging.2021.10.007 [epub ahead of print].
• ABSTRACT: Qaderi V, Ball J, Nehme Z, Neumann JT, Wolfe R, Woods R, Tonkin AM, Smith K, McNeil JJ. Out-of-hospital cardiac arrest in elderly individuals. Eur Heart J. 2021; Oct 14, doi: 10.1093/eurheartj/ehab724.1541.
• Craig HJ, Ryan J, Freak-Poli R, Owen A, McNeil J, Woods R, Ward S, Britt C, Gasevic D. Dispositional Optimism and All-Cause Mortality in Older Adults: A Cohort Study. Psychosom Med. 2021; Oct 1 ;83(8):938-945. doi: 10.1097/PSY.0000000000000989 PMID: 34334727.
• Yan MK, Wolfe R, Orchard SG, Ernst ME, Mar VJ. Effect of methotrexate on melanoma risk in older adults: Secondary analysis of a randomised controlled trial. Australas J Dermatol. 2021; Sep 28, doi: 10.1111/ajd.13727 [epub] PMID: 34581443; PMCID: PMC9265764.
• Lin X, Banaszak-Holl J, Xie J, Ward SA, Brodaty H, Storey E, Shah RC, Murray A, Ryan J, Orchard SG, Fitzgerald SM, McNeil JJ. Similar mortality risk in incident cognitive impairment and dementia: Evidence from the ASPirin in Reducing Events in the Elderly (ASPREE) trial. J Am Geriatrics Soc. 2021; Sept 17, doi: 10.1111/jgs.17435.
• Ernst ME, Fravel MA, Webb KL, Wetmore JB, Wolfe R, Chowdhury E, Reid CM, Woods RL, Beilin L, Margolis KL, Murray AM, Polkinghorne KR; ASPirin in Reducing Events in the Elderly Investigator Group. Long-term Blood Pressure Variability and Kidney Function in Participants of the ASPREE Trial. Am J Hypertens. 2021; Sept. 14, doi: 10.1093/ajh/hpab143 [epub ahead of print]. Accompanying EDITORIAL 2021; Oct 8, doi: doi.org/10.1093/ajh/hpab160.
• Fransquet PD, Lacaze P, Saffery R, Shah RC, Vryer R, Murray A, Woods RL, Ryan J. Accelerated Epigenetic Aging in Peripheral Blood Does not Predict Dementia Risk. Curr Alzheimer Res. 2021; Aug. 22, doi: 10.2174/1567205018666210823100721 [epub ahead of print]. PMID: 34429046
• Huq AJ, Fulton-Howard B, Riaz M, Laws S, Sebra R, Ryan J; Alzheimer’s Disease Genetics Consortium, Renton AE, Goate AM, Masters CL, Storey E, Shah RC, Murray A, McNeil J, Winship I, James PA, Lacaze P. Polygenic score modifies risk for Alzheimer’s disease in APOE ε4 homozygotes at phenotypic extremes. Alzheimers Dement (Amst). 2021; Aug. 5, doi: 10.1002/dad2.12226. eCollection 2021.
• Ryan J, Espinoza S,  Ernst ME, Saifuddin Ekram ARM, Wolfe R, Murray AM, Shah RC, Orchard SG, Fitzgerald S, Beilin LJ, Ward SA, Williamson JD, Newman AB, McNeil JJ, Woods RL, on behalf of the ASPREE Investigator Group. Validation of a deficit-accumulation Frailty Index in the ASPREE study and its predictive capacity for disability-free survival. Journals of Gerontology: Series A. 2021; Aug. 02, doi.org/10.1093/gerona/glab225.
• Lacaze P, Riaz M, Sebra R, Hooper AJ, Pang J, Tiller J, Polekhina G, Tonkin A, Reid C, Zoungas S, Murray AM, Nicholls S, Watts G, Schadt E, McNeil JJ. Protective lipid-lowering genetic variants in healthy older individuals without coronary heart disease. Open Heart. 2021; Aug. 02, doi: 10.1136/openhrt-2021-001710.
• Lacaze P, Bakshi A, Riaz M, Orchard SG, Tiller J, Neumann JT, Carr PR, Joshi AD, Cao Y, Warner ET, Manning A, Nguyen-Dumont T, Southey MC, Milne RL, Ford L, Sebra R, Schadt E, Gately L, Gibbs P, Thompson BA, Macrae FA, James P, Winship I, McLean C, Zalcberg JR, Woods RL, Chan AT, Murray AM, McNeil JJ. Genomic Risk Prediction for Breast Cancer in Older Women. Cancers. 2021 July 14; 13(14):3533, doi.org/10.3390/cancers13143533.
• Hu J, Fitzgerald SM, Owen AJ, Ryan J, Joyce J, Chowdhury E, Reid CM, Britt C, Woods RL, McNeil JJ, Freak-Poli R. Social isolation, social support, loneliness and cardiovascular disease risk factors: a cross-sectional study among older adults. Int J Geriatr Psychiatry. 2021 July 7; 1-15, doi: /10.1002/gps.5601.
• Phyo AZZ, Ryan J, Gonzalez-Chica DA, Stocks NP, Reid CM, Tonkin AM, Woods RL, Nelson MR, Murray AM, Gasevic D, Freak-Poli R. Health-related quality of life and incident cardiovascular disease events in community-dwelling older people: A prospective cohort study. International Journal of Cardiology. 2021, doi: /10.1016/j.ijcard.2021.07.004 [published online, 2021 July 7].
• Zhou Z, Ryan J, Ernst ME, Zoungas S, Tonkin AM, Woods RL, McNeil JJ, Reid CM, Curtis AJ, Wolfe R, Wrigglesworth J, Shah RC, Storey E, Murray A, Orchard SG, Nelson MR. Effect of statin therapy on cognitive decline and incident dementia in older adults, J Am Coll Cardiol 2021 June 29; 77(25): 3145-56, doi:10.1016/j.jacc.2021.04.075.
• Ernst ME, Ryan J, Chowdhury EK, Margolis KL, Beilin LJ, Reid CM, Nelson MR, Woods RL, Shah RC, Orchard SG, Wolfe R, Storey E, Tonkin AM, Brodtmann A, McNeil JJ, Murray AM. Long-Term Blood Pressure Variability and Risk of Cognitive Decline and Dementia Among Older Adults. J Am Heart Assoc 2021, June 26 ;10:e019613, doi: 10.1161/JAHA.120.019613.
• Lacaze P, Sebra R, Riaz M, Ingles J, Tiller J, Thompson BA, James PA, Fatkin D, Semsarian C, Reid CM, Tonkin AM, Winship I, Schadt E, McNeil JJ. Genetic variants associated with inherited cardiovascular disorders among 13,131 asymptomatic older adults of European descent. NPJ Genom Med. 2021 June 16; 6(1):51, doi: 10.1038/s41525-021-00211-x. PMID: 34135346; PMCID: PMC8209162.
• Neumann JT, Riaz M, Bakshi A, Polekhina G, Thao LTP, Nelson MR, Woods RL, Abraham G, Inouye M, Reid CM, Tonkin AM, Williamson JD, Donnan G, Brodtmann A, Cloud GC, McNeil JJ, Lacaze P. Predictive performance of a polygenic risk score for incident ischemic stroke in a healthy older population. Stroke 2021;52, doi:10.1161/STROKEAHA.120.033670 [epub ahead of print, May 27].
• Riaz M, Huq A, Ryan J, Orchard SG, Tiller J, Lockery J, Woods RL, Wolfe R, Renton AE, Goate AM, Sebra R, Schadt E, Brodtmann A, Shah RC, Storey E, Murray AM, McNeil JJ, Lacaze P. Effect of APOE and a polygenic risk score on incident dementia and cognitive decline in a healthy older population. Aging Cell. 2021, doi: 10.1111/acel.13384. [epub ahead of print, May 26] PMID: 34041846.
• Nunn JS, Sulovski M, Tiller J, Holloway B, Ayton D, Lacaze P. Involving elderly research participants in the co-design of a future multi-generational cohort study. Research Involvement and Engagement 7:23. 2021 May 3, doi.org/10.1186/s40900-021-00271-4
• Wu Z, Woods RL, Wolfe R, Storey E, Chong TTJ, Shah RC, Orchard SG, McNeil JJ, Murray AM, Ryan J; the ASPREE Investigator Group. Trajectories of cognitive function in community‐dwelling older adults: A longitudinal study of population heterogeneity. Alzheimer’s Dement. 2021 May 2,  doi: org/10.1002/dad2.12180.
• Muhandiramge J, Orchard S, Haydon A, Zalcberg J. The acceleration of ageing in older patients with cancer. J Geriatr Oncol. 2021; April, doi: 10.1016/j.jgo.2020.09.010. [epub 2020 Sep 12]. PMID: 32933870
• Bakshi A, Yan M, Riaz M, Polekhina G, Orchard SG, Tiller J, Wolfe R, Joshi A, Cao Y, McInerney-Leo AM, Yanes T, Janda M, Soyer HP, Cust AE, Law MH, Gibbs P, McLean C, Chan AT, McNeil JJ, Mar VJ, Lacaze P. Genomic Risk Score for Melanoma in a Prospective Study of Older Individuals. J Natl Cancer Inst. 2021, doi: 10.1093/jnci/djab076 [epub ahead of print, 2021 April 10].
• Nguyen-Dumont T, Dowty JG, MacInnis RJ, Steen JA, Riaz M, Dugue PA, Renault AL, Hammet F, Mahmoodi M, Theys D, Tsimiklis H, Severi G, Bolton D, Lacaze P, Sevra R, Schadt E, McNeil J, Giles GG, Milne RL, Southey MC. Rare germline pathogenic variants identified by multigene panel testing and the risk of aggressive prostate cancer. Cancers 2021; Mar. 24, doi: 10.3390/cancers13071495.
• Lockery JE, Broder JC, Ryan J, Stewart AC, Woods RL, Chong TT, Cloud GC, Murray A, Rigby JD, Shah R, Storey E, Ward SA, Wolfe R, Reid CM, Collyer TA, Ernst ME; the ASPREE Investigator Group. A Cohort Study of Anticholinergic Medication Burden and Incident Dementia and Stroke in Older Adults. J Gen Intern Med. 2021, doi: 10.1007/s11606-020-06550-2 [published online, 2021 Mar. 22]. PMID: 33754317
• Phyo AZZ, Gonzalez-Chica DA, Stocks NP, Storey E, Woods RL, Murray AM, Orchard SG, Shah RC, Gasevic D, Freak-Poli R, Ryan J; ASPREE Investigator Group. The Utility of Assessing Health-Related Quality of Life to Predict Cognitive Decline and Dementia. J Alzheimers Dis. 2012, doi: 10.3233/JAD-201349 [epub ahead of print 2021 Feb. 12]. PMID: 33579847
• EDITORIAL McNeil JJ. Aspirin and primary prevention of colorectal cancer: a still evolving story. JNCI: Journal of the National Cancer Institute, 2021;djab010, doi.org/10.1093/jnci/djab010 [published online, 2021 Feb. 02].
• Berk M, Agustini B, Woods RL, Nelson MR, Shah RC, Reid CM, Storey E, Fitzgerald S, Lockery JE, Wolfe R, Mohebbi M, Dodd S, Murray AM, Stocks N, Fitzgerald P, Mazza C, McNeil JJ. Effects of aspirin on the long-term management of depression in older people: a double-blind randomised placebo-controlled trial. Mol Psychiatry 2021,  doi.org/10.1038/s41380-021-01020-5 [published online, 2021 Jan. 27].
• Orchard ER, Ward PGD, Chopra S, Storey E, Egan GF, Jamadar SD. Neuroprotective Effects of Motherhood on Brain Function in Late Life: A Resting-State fMRI Study. Cereb Cortex. 2021; Jan 5, doi: 10.1093/cercor/bhaa293 PMID: 33067999; PMCID: PMC7906778.
• Phyo AZZ, Ryan J, Gonzalez-Chica DA, Woods RL, Reid CM, Nelson MR, Murray AM, Gasevic D, Stocks NP, Freak-Poli R; the ASPREE Investigator Group. Health-related quality of life and all-cause mortality among older health individuals in Australia and the United States: a prospective cohort study. Quality of Life Research 2021; 30(4):1037-48, doi:10.1007/s11136-020-02723-y [published online, 2021 Jan. 03].

2020

• Woods RL, Espinoza S, Thao LTP, Ernst ME, Ryan J, Wolfe R, Shah RC, Ward SA, Storey E, Nelson MR, Reid CM, Lockery JE, Orchard SG, Trevaks RE, Fitzgerald SM, Stocks NP, Williamson JD, McNeil JJ, Murray AM, Newman AB; ASPREE Investigator Group. Effect of Aspirin on Activities of Daily Living Disability in Community-Dwelling Older Adults. J Gerontol A Biol Sci Med Sci. 2020; glaa316, doi:10.1093/gerona/glaa316 [published online ahead of print, 2020 Dec. 26].
• Islam RM, Bell RJ, Handelsman DJ, Robinson PJ, Wolfe R, Davis SR; ASPREE Investigator Group. Longitudinal changes over three years in sex steroid hormone levels in women aged 70 years and over. Clin Endocrinol (Oxf). 2020; Dec. 22, doi: 10.1111/cen.14401 [epub ahead of print]. PMID: 33351205
• Lefevre A, Hopper I, McNeil JJ, Owen A; ALSOP Complementary Medicine Research Group. Complementary medicine use by community-dwelling older Australians [published online ahead of print, 2020 Dec 10]. Med J Aust. 2020; 10.5694/mja2.50884, doi:10.5694/mja2.50884 [published online ahead of print, 2020 Dec. 9].
• Gilmartin-Thomas JF, Forbes A, Liew D, McNeil JJ, Cicuttini FM, Owen AJ, Ernst ME, Nelson MR, Lockery J, Ward SA, Busija L; ASPREE Investigator Group. Evaluation of the Pain Impact Index for community-dwelling older adults through the application of Rasch modelling. Pain Pract. 2020; Dec. 9, doi: 10.1111/papr.12980 [epub ahead of print]. PMID: 33295122
• Chowdhury EK, Ernst ME, Nelson M, Margolis K, Beilin LJ, Johnston C, Woods R, Murray A, Wolfe R, Storey E, Shah RC, Lockery J, Tonkin A, Newman A, Abhayaratna W, Stocks N, Fitzgerald S, Orchard S, Trevaks R, Donnan G, Grimm R, McNeil J, Reid CM; ASPREE Investigator Group. Impact of the 2017 American Heart Association and American College of Cardiology hypertension guideline in aged individuals. J Hypertens. 2020 Dec;38(12):2527-2536, doi: 10.1097/HJH.0000000000002582. PMID: 32740404; PMCID: PMC8218338.
• Tiller J, Trainer AH, Campbell I, Lacaze PA. Ethical and practical implications of returning genetic research results: two Australian case studies. Med J Aust. 2020; Nov 08, doi: 10.5694/mja2.50842 [epub].
• Ernst ME, Chowdhury EK, Beilin LJ, Margolis KL, Nelson MR, Wolfe R, Tonkin AM, Ryan J, Woods RL, McNeil JJ, Reid CR, for the ASPREE Investigator Group. Long-Term Blood Pressure Variability and Risk of Cardiovascular Disease Events Among Community-Dwelling Elderly. Hypertension, doi:10.1161/HYPERTENSIONAHA.120.16209 [published online 2020 Nov. 2].
• Lockery JE, Ernst ME, Broder JC, Orchard SG, Murray A, Nelson MR, Stocks NP, Wolfe R, Reid CM, Liew D, Woods RL; ASPREE Investigator Group. Prescription Medication Use in Older Adults Without Major Cardiovascular Disease Enrolled in the Aspirin in Reducing Events in the Elderly (ASPREE) Clinical Trial. Pharmacotherapy 2020; Oct;40(10):1042-1053, doi:10.1002/phar.2461.
• Robman LD, Thao LTP, Guymer RH, Wolfe R, Woods RL, Hodgson LAB, Phung J, Makeyeva GA, Le-Pham YA, Orchard SG, Suleiman J, Maguire E, Trevaks RE, Ward SA, Riaz M, Lacaze P, Elsdon S, Abhayaratna WP, Nelson MR, Ernst ME, Reid CM, McNeil JJ; ASPREE Investigator Group. Baseline characteristics and age-related macular degeneration in participants of the “ASPirin in Reducing Events in the Elderly” (ASPREE)-AMD trial. Contemporary Clinical Trials Communications 2020; 20: 100667,  doi:10.1016/jconctc.2020.100667 [published online 2020 Oct. 11].
• Eisen DP, Leder K, Woods RL, Lockery JE, McGuinness SL, Wolfe R, Pilcher D, Moore EM, Shastry A, Nelson MR, Reid C, McNeil, JJ, McBryde ES. Effect of aspirin on deaths associated with sepsis in healthy older people (ANTISEPSIS): a randomised, double-blind, placebo-controlled primary prevention trial. The Lancet Respiratory Medicine 2020, doi.org/10.1016/S2213-2600(20)30411-2 [published online 2020 Sept. 17].
• Gilmartin-Thomas JFM, Ernst ME, Nelson MR, Lockery JE, Ward SA, Woods RL, Britt C, Murray A, Workman B, McNeil JJ; ASPREE Investigator Group. Musculoskeletal Pain Experienced on Most Days is a Common Accompaniment of Ageing amongst Community-Dwelling Older Australians: A Questionnaire-Based Study. Journal of Aging and Health 2020, doi:10.1177/0898264320952914 [pre-print published online 2020 Sept. 11].
• Wolfe R, Wetmore JB, Wood RL, McNeil JJ, Gallagher H, Roderick P, Walker R, Nelson MR, Reid CM, Shah RC, Ernst ME, Lockery JE, Tonkin AM, Abhayaratna WP, Gibbs P, Wood EM, Mahady SE, Williamson JD, Donnan GA, Cloud GC, Murray AM, Polkinghorne K, for the ASPREE Investigator Group. Subgroup analysis of the ASPirin in Reducing Events in the Elderly randomized clinical trial suggest aspirin did not improve outcomes in older adults with chronic kidney disease. Kidney International 2020, doi.org/10.1016/j.kint.2020.08.011  [published online 2020 Sept. 10].
• Gilmartin-Thomas JFM, Cicuttini FM, Owen AJ, Wolfe R, Ernst ME, Nelson MR, Lockery J, Woods RL, Britt C, Liew D, Murray A, Workman B, Ward SA, McNeil JJ; ASPREE Investigator Group. Moderate or severe low back pain is associated with body mass index amongst community-dwelling older Australians. Arch Gerontol & Geriatrics 91; Nov-Dec 2020, 104231, doi:10.1016/j.archger.2020.104231 [published online 2020 Aug. 13].
• McNeil JJ, Gibbs P, Orchard SG, Lockery JE, Bernstein WB, Cao Y, Ford L, Haydon A, Kirpach B, Macrae F, McLean C, Millar J, Murray AM, Nelson MR, Polekhina G, Reid CM, Richmond E, Rodríguez LM, Shah RC, Tie J, Umar A, van Londen GJ, Ronaldson K, Wolfe R, Woods RL, Zalcberg J, Chan A, for the ASPREE investigator Group. Effect of aspirin on cancer incidence and mortality in older adults. JNCI: Journal of the National Cancer Institute, djaa114, doi.org/10.1093/jnci/djaa114 [accepted manuscript published online 2020 Aug. 11].
• Ryan J, Woods RL, Britt CJ, Murray AM, Shah RC, Reid CM, Wolfe R, Nelson MR, Orchard SG, Lockery JE, Trevaks RE, Storey E, for the ASPREE Investigator Group. Normative Data for the Symbol Digit Modalities Test in Older White Australians and Americans, African-Americans, and Hispanic/Latinos. J Alzheimer’s Disease Reports 2020;4: 313-23, doi: 10.3233/ADR-200194. [published online 2020 Aug. 04].
• Mahady SE, Margolis KL, Chan A, Polekhina G, Woods RL, Wolfe R, Nelson MR, Lockery JE, Wood EM, Reid C, Ernst ME, Murray A, Thao LTP, McNeil JJ. Major GI bleeding in older persons using aspirin: incidence and risk factors in the ASPREE randomised controlled trial. Gut 2020, doi:10.1136/gutjnl-2020-321585 [published online 2020 Aug. 03].
• LETTER: Mahady SE, Woods RL, Wolfe R, Nelson MR, Murray AM, McNeil JJ. Aspirin for Primary Prevention in Adults Older than 70 Years is Not Supported by High-Quality Trial Data and May Cause Harm. Am J Med. 2020; Jul, doi: 10.1016/j.amjmed.2020.02.031 PMID: 32600553; PMCID: PMC9588393.
• Orchard SG, Lockery JE, Gibbs P, Polekhina G, Wolfe R, Zalcberg J, Haydon A, McNeil JJ, Nelson MR, Reid CM, Kirpach B, Murray AM, Woods RL, for the ASPREE investigator Group. Cancer history and risk factors in healthy older people enrolling in the ASPREE clinical trial. Contemporary Clinical Trials 2020; Sept. doi.org/10.1016/j.cct.2020.106095 [published online 2020 Jul 31].
• Orchard ER, Ward PGD, Sforazzini F, Storey E, Egan G, Jamadar SD. Relationship between parenthood and cortical thickness in late adulthood. PLoS One 2020; 15(7):e0236031, doi:10.1371/journal.pone.0236031 [published online 2020 Jul 28].
• Ward PDG, Orchard ER, Oldham S, Arnatkevičiūtė A, Sforazzini F, Fornito A, Storey E, Egan G, Jamadar SD. Individual differences in haemoglobin concentration influence bold fMRI functional connectivity and its correlation with cognition. NeuroImage 2020; 221:117196, doi:10.1016/j.neuroimage.2020.117196 [published online ahead of print 2020 Jul 25].
• Ernst ME, Chowdhury EK, Nelson MR, Reid CM, Margolis KL, Beilin LJ, Stocks N, Murray AM, Wolfe R, Lockery JE, Orchard SG, Woods RL, McNeil JJ; the ASPREE Investigator Group. Antihypertensive medications use and blood pressure control among treated older adults. J Clin Hypertens. 2020; 00: 1– 9, doi.org/10.1111/jch.13934 [published online 2020 Jul 15].
• Fransquet PD, Lacaze P. Saffery R, Phung J, Parker E, Shah R, Murray A, Woods RL, Ryan J. Blood DNA methylation signatures to detect dementia prior to overt clinical symptoms. Alzheimer’s & Dementia 2020; 12:e12056,  doi: 10.1002/dad2.12056 [published online 2020 Jul 7].
• Davis SR, Garcia AM, Robinson PJ, Handelsman DJ, Desai R, Wolfe R, Bell RJ, the ASPREE Investigator Group, Estrone is a strong predictor of circulating estradiol in women aged 70 years and older, The Journal of Clinical Endocrinology & Metabolism, 2020; dgaa429, doi.org/10.1210/clinem/dgaa429 [accepted manuscript 2020 July 02].
• Lacaze P, Sebra R, Riaz M, Tiller J, Revote J, Phung J, Parker EJ, Orchard SG, Lockery JE, Wolfe R, Strahl M, Wang YC, Chen R, Sisco D, Arnold T, Thompson BA, Buchanan DD, Macrae FA, James PA, Abhayaratna WP, Lockett TJ, Gibbs P, Tonkin AM, Nelson MR, Reid CM, Woods RL, Murray AM, Winship I, McNeil JJ, Schadt E. Medically actionable pathogenic variants in a population of 13,131 healthy elderly individuals. Genet Med. 2020; Nov;22(11):1883-1886, doi: 10.1038/s41436-020-0881-7 [epub 2020 July 1]. PMID: 32606442; PMCID: PMC7606791
• Zhou Z, Ofori-Asenso R, Curtis A, Breslin M, Wolfe R, McNeil JJ, Murray AM, Ernst ME, Reid CM, Lockery JE, Woods RL, Tonkin AM, Nelson MR. Association of Statin Use with Disability-Free Survival and Cardiovascular Disease among Healthy Older Adults. J Amer Coll Cardiol. 2020; Jun 30; 76: 17-27, doi:10.1016/j.jacc.2020.05.016.
• Lewis JP, Riaz M, Xie S, Polekhina G, Wolfe R, Nelson M, Tonkin AM, Reid CM, Murray AM, McNeil JJ, Shuldiner AR, Lacaze P. Genetic variation in PEAR1, cardiovascular outcomes and effects of aspirin in a healthy elderly population. Clin Pharmacol Ther. 2020, doi: 10.1002/cpt.1959 [online ahead of print 2020 Jun 20]. PMID: 32562573
• Lacaze P, Sebra R, Riaz M, Hooper AJ, Tiller J, Bakshi A, Woods RL, Tonkin AM, Reid CM, Murray AM, Nicholls SJ, Watts GF, Schadt E, McNeil JJ. Familial Hypercholesterolemia in a Healthy Elderly Population. Circ Genom Precis Med. 2020; June 10, doi:10.1161/CIRCGEN.120.002938 [epub ahead of print].
• Berk M, Woods RL, Nelson MR, Shah RC, Reid CM, Storey E, Fitzgerald S, Lockery JE, Wolfe, R, Mohebbi M, Dodd S, Murray AM, Stocks N, Fitzgerald P, Mazza C, Agustini B, McNeil JJ.  Effect of Aspirin vs Placebo on the Prevention of Depression in Older People: A Randomized Clinical Trial. JAMA Psychiatry 2020, doi:10.1001/jamapsychiatry.2020.1214 [published online 2020 Jun 03].
• Agustini B, Lotfaliany M, Woods RL, McNeil JJ, Nelson MR, Shah RC, Murray AM, Ernst M, Reid CM, Tonkin A, Storey E, Lockery JE, Williams LJ, Berk M, Mohebbi M, on behalf of the ASPREE investigators. Patterns of association between depressive symptoms and chronic medical morbidities in older adults. J Amer Geriatrics Soc. 2020, doi 10.1111/jgs.16468. [published online 2020 May 13].
• Woods RL, Polekhina G, Wolfe R, Nelson MR, Ernst ME, Reid CM, Shah RC, Lockery JE, Orchard SG, Murray AM, McNeil JJ, on behalf of the ASPREE Investigator Group. No modulation of aspirin’s effect by body weight in healthy older men and women. Circulation 2020; Mar. 30, doi.org/10.1161/CIRCULATIONAHA.119.044142.
• Ryan J, Storey E, Murray AM, Woods RL, Wolfe R, Reid CM, Nelson MR, Chong T, Williamson JD, Ward SA, Lockery JE, Orchard SG, Trevaks R, Kirpach B, Newman AB, Ernst ME, McNeil JJ, Shah RC. Randomized Placebo-controlled Trial of the effects of Aspirin on Dementia and Cognitive Decline. Neurology 2020; Mar. 25, doi.org/10.1212/WNL.0000000000009277.
• Barker AL, Soh SE, Sanders KM, Pasco J, Khosla S, Ebeling PR, Ward SA, Peeters G, Talevski J, Cumming RG, Seeman E, McNeil JJ. Aspirin and fracture risk: a systematic review and exploratory meta-analysis of observational studies. BMJ Open 2020; Feb. 20;10(2):e026876, doi: 10.1136/bmjopen-2018-026876.
• Ryan J, Woods RL, Murray AM, Shah RC, Britt C, Reid CM, Wolfe R, Nelson MR, Lockery JE, Orchard SG, Trevaks R, Chong T, McNeil JJ, Storey E.  Normative Performance of Older Individuals on the Hopkins Verbal Learning Test-Revised (HVLT-R) According to Ethno-Racial Group, Gender, Age and Education Level. The Clinical Neuropsychologist 2020; Feb. 26, doi:10.1080/13854046.2020.1730444.
• Agustini B, Mohebbi M, Woods RL, McNeil JJ, Nelson MR, Shah RC, Murray AM, Ernst ME, Reid CM, Tonkin A, Lockery JE, Berk M, on behalf of the ASPREE Investigator Group. The association of antihypertensive use and depressive symptoms in a large older population with hypertension living in Australia and the United States. Journal of Human Hypertension 2020; Pubmed 32001828,  doi.org/10.1038/s41371-020-0303-y.
• Pinese M, Lacaze P, Rath E, Stone A, Brion MJ, Ameur A, Nagpal S, Puttick C, Husson S, Degrave D, Navin Cristina T, Kahl VS, Statham A, Woods R, McNeil J, Riaz M, Barr M, Nelson M, Reid C, Murray A, Shah R, Wolfe R, Atkins J, Fitzsimmons C, Cairns H, Green M, Carr V, Cowley M, Pickett H, James P, Powell J, Kaplan W, Gibson G, Gyllensten U, Cairns M, McNamara M, Dinger M, Thomas D. The Medical Genome Reference Bank contains whole genome and phenotype data of 2,570 healthy elderly. Nature Communications Online 2020; Jan. 23, doi:10.1038/s41467-019-14079-0.
• Voskoboinik I, Lacaze P, Jang HS, Flinsenberg TWH, Fernando SL, Kerridge I, Riaz M, Sebra R, Thia KYT, Noori T, Schadt EE, McNeil JJ, Trapani JA. Prevalence and Disease Predisposition of p.A91V perforin in an aged Caucasian Population. Blood Journal 2020, doi:10.1182/blood-2019003487 [epub ahead of print 2020 Jan. 13].

2019

• Lockery JE, Rigby J, Collyer TA, Stewart A, Woods RL, McNeil JJ, Reid CM, Ernst ME, on behalf of the ASPREE Investigator Group. Optimising medications data collection in a large-scale clinical trial. Plos One  2019; 14 (12), doi.org/10.1371/journal.pone.0226868.
• Chowdhury EK, Nelson MR, Ernst ME, Margolis KL, Beilin LJ, Johnston CI, Woods RL, Murray AM, Wolfe R, Storey E, Shah RC, Lockery JE, Tonkin AM, Newman AB, Williamson JD, Abhayaratna WP, Stocks NP, Fitzgerald SM, Orchard SG, Trevaks RE, Donnan GA, Grimm R, McNeil JJ, Reid CM, for the ASPREE investigator Group. Factors associated with treatment and control of hypertension in a healthy elderly population free of cardiovascular disease: a cross-sectional study. American Journal of Hypertension 2019; Dec. 06, doi.org/10.1093/ajh/hpz192.
• Jamadar SD, Sforazzini F, Raniga P, Ferris NJ, Paton B, Bailey MJ, Brodtmann A, Yates PA, Donnan GA, Ward SA, Woods RL, Storey E, McNeil JJ, Egan GF;  ASPREE Investigator Group. Sexual Dimorphism of Resting-State Network Connectivity in Healthy Ageing. The journals of gerontology. Series B, Psychological sciences and social sciences 2019; 74 (7): 1121-1131, doi:10.1093/geronb/gby004.
• Lockery JE, Collyer TA, Reid CM, Ernst ME, Gilbertson D, Hay N, Kirpach B, McNeil JJ, Nelson MR, Orchard SG, Pruksawongsin K, Shah RC, Wolfe R, Woods RL, on behalf of the ASPREE Investigator Group. Overcoming challenges to data quality in the ASPREE clinical trial. Trials 2019; 20: 686, doi:10.1186/s13063-019-3789-2.
• Davis SR, Bell RJ, Robinson PJ, Handelsman DJ, Gilbert T, Phung J, Desai R, Lockery JE, Woods RL, Wolfe RS, Reid CM, Nelson  MR, Murray AM, McNeil JJ. Testosterone and estrone increase from the age of 70 years; findings from the Sex Hormones in Older Women Study. J Clinical Endocrinology & Metabolism 2019; Aug. 13; pii: jc.2019-00743, doi: 10.1210/jc.2019-00743 [epub ahead of print].
• Agustini B, Mohebbi M, Woods RL, McNeil JJ, Nelson MR, Shah RC, Murray AM, Ernst ME, Reid CM, Tonkin A, Lockery JE, Berk M; ASPREE Investigator Group. Association Between Statin Use and Depressive Symptoms in a Large Community-Dwelling Older Population Living in Australia and the USA: A Cross-Sectional Study. CNS Drugs 2019; May 6, doi: 10.1007/s40263-019-00633-3 [epub ahead of print].
• Polkinghorne KR, Wolfe R, Jachno KM, Wetmore JB, Woods RL, McNeil JJ, Nelson MR, Reid CM, Murray AM; ASPREE Investigator Group. Prevalence of chronic kidney disease in the elderly using the ASPirin in Reducing Events in the Elderly study cohort. Nephrology 2019; 24:1248-1256, doi: 10.1111/nep.13565.
• Mohebbi M, Agustini B, Woods RL, McNeil JJ, Nelson MR, Shah RC, Nguyen V, Storey E, Murray AM, Reid CM, Kirpach B, Wolfe RS, Lockery JE, Berk M; ASPREE Investigator Group. Prevalence of depressive symptoms and its associated factors among healthy community-dwelling older adults living in Australia and the United States. Int J Geriatr Psychiatry 2019; Apr. 16, doi: 10.1002/gps.5119 [epub ahead of print].
• Lockery JE, Collyer TA, Abhayaratna WP, Fitzgerald SM, McNeil JJ, Nelson MR, Orchard SG, Reid C, Stocks NP, Trevaks RE, Woods RL. Recruiting general practice patients for large clinical trials: lessons from the Aspirin in Reducing Events in the Elderly (ASPREE) study. Med J Aust 2019; 210 (4): 168-173, doi: 10.5694/mja2.12060.
• CORRESPONDENCE McNeil JJ, Woods RL, Murray AM, for the ASPREE Investigator Group. Effects of aspirin in the healthy elderly. Correspondence. N Engl J Med 2019; 380 (18): 1776-7, doi:10.1056/NEJMc1901774.
• COMMENTARY Chan AT, McNeil J. Aspirin and Cancer Prevention in the Elderly: Where Do We Go From Here? Gastroenterology. 2019 Feb; 156(3):534-538, doi: 10.1053/j.gastro.2018.11.063.
• McNeil JJ, Woods RL, Ward SA, Britt CJ, Lockery JE, Beilin LJ, Owen AJ. Cohort Profile: The ASPREE Longitudinal Study of Older Persons (ALSOP). International Journal of Epidemiology 2019, doi.org/10.1093/ije/dyy279.

2018

• Lacaze P, Pinese M, Kaplan W, Stone A, Brion M, Woods RL, McNamara M, McNeil JJ, Dinger ME, Thomas DM. The Medical Genome Reference Bank: a whole-genome data resource of 4,000 healthy elderly individuals. Rationale and cohort design. European Journal of Human Genetics 2018, doi: 10.1038/s41431-018-0279-z.
• Stocks N, González-Chica DA, Lockery JE, Shah RC, Murray AM, Wolfe R, Nelson MR, Reid CM, McNeil JJ, Woods RL, on behalf of the ASPREE Investigator Group. Quality of Life for 19,114 participants in the ASPREE (Aspirin in Reducing Events in the Elderly) Study and their association with sociodemographic and lifestyle modifiable risk factors. Quality of Life Research 2018, pp.1-12, doi: 10.1007/s11136-018-2040-z.
• McNeil JJ*, Woods RL*, Nelson MR, Reid CM, Kirpach B, Wolfe R, Storey E, Shah RC, Lockery JE, Tonkin AM, Newman AB, Williamson JD, Margolis KL, Ernst ME, Abhayaratna WP, Stocks N, Fitzgerald SM, Orchard SG, Trevaks RE, Beilin LJ, Donnan GA, Gibbs P, Johnston CI, Ryan J, Radziszewska B, Grimm R & Murray AM, on behalf of the ASPREE Investigator Group (* joint first authors). Effect of aspirin on disability-free survival in the healthy elderly. New England Journal of Medicine 2018; 379:1499-1508, doi: 10.1056/nejmoa1800722 [published online Sept. 2018].
• McNeil JJ*, Nelson MR*, Woods RL, Lockery JE, Wolfe R, Reid CM, Kirpach B, Shah RC, Ives DG, Storey E, Ryan J, Tonkin AM, Newman AB, Williamson JD, Margolis KL, Ernst ME, Abhayaratna WP, Stocks N, Fitzgerald SM, Orchard SG, Trevaks RE, Beilin LJ, Donnan GA, Gibbs P, Johnston CI, Radziszewska B, Grimm R & Murray AM, on behalf of the ASPREE Investigator Group (* joint first authors). Effect of aspirin on all-cause mortality in the healthy elderly. New England Journal of Medicine 2018; 379:1499-1508, doi: 10.1056/NEJMoa1803955 [published online Sept. 2018].
• McNeil JJ, Wolfe R, Woods RL, Tonkin AM, Donnan GA, Nelson MR, Reid CM, Lockery JE, Kirpach B, Storey E, Shah RC, Williamson JD, Margolis KL, Ernst ME, Abhayaratna WP, Stocks N, Fitzgerald SM, Orchard SG, Trevaks RE, Beilin LJ, Johnston CI, Ryan J, Radziszewska B, Jelinek M, Malik M, Eaton C, Brauer D, Cloud G, Wood E, Mahady SE, Satterfield S, Grimm R & Murray AM, on behalf of the ASPREE Investigator Group. Effect of aspirin on cardiovascular events and bleeding in the healthy elderly. New England Journal of Medicine 2018; 379:1499-1508, doi: 10.1056/nejmoa1805819 [published online Sept. 2018].
• Ryan J, Woods RL, Britt C, Murray AM, Shah RC, Reid CM, Kirpach B, Wolfe RS, Nelson MR, Lockery JE, Orchard SG, Trevaks RE, McNeil JJ, Storey E, on behalf of the ASPREE Investigator Group. Normative performance of healthy older individuals on the Modified Mini-Mental State (3MS) examination according to ethno-racial group, gender, age, and education level. The Clinical Neuropsychologist 2018, doi.org/10.1080/13854046.2018.1488996 [published online July 2018].
• Margolis KL, Mahady SE, Nelson MR, Ives DG, Satterfield S, Britt C, Ekram S, Lockery JE, Schwartz EC, Woods RL, McNeil JJ, Wood EM. Development of a standardized definition for clinically significant bleeding in the ASPirin in Reducing Events in the Elderly (ASPREE) trial. Contemporary Clinical Trials Communications 2018; Vol 11, 30-36, doi.org/10.1016/j.conctc.2018.05.015.
• Wolfe R, Murray AM, Woods, RL, Kirpach B, Gilbertson D, Shah RC, Nelson MR, Reid CM, Ernst ME, Lockery JE, Donnan GA, Williamson J, McNeil JJ. The aspirin in reducing events in the elderly trial: Statistical analysis plan. International Journal of Stroke 2018; Vol.13(3), pp.335-338, doi.org/10.1177/1747493017741383.
• Fransquet PD, Lacaze P, Woods RL, McNeil JJ, Saffery R, Ryan J. Blood DNA methylation as a potential biomarker of dementia: a systematic review. Alzheimer’s & Dementia 2017; 14(1): 81-103. IF:11.0, doi: 10.1016/j.jalz.2017.10.002.
• Ward SA, Storey E, Woods RL, Hamilton GS, Kawasaki R, Janke AL, Naughton MT, O’Donoghue F, Wolfe R, Wong TY, Reid CM, Abhayaratna WP, Stocks N, Trevaks R, Fitzgerald S, Hodgson LAB, Robman L, Workman B, Mcneil JJ. The Study of Neurocognitive Outcomes, Radiological and Retinal Effects of Aspirin in Sleep Apnoea- rationale and methodology of the SNORE-ASA study. Contemporary clinical trials 2018; Vol.64, pp.101-111, doi.org/10.1016/j.cct.2017.10.016.
• Mohebbi M, Nguyen V, McNeil JJ, Woods RL, Nelson MR, Shah RC, Storey E, Murray AM, Reid CM, Kirpach B, Wolfe, R, Lockery JE, Berk M, on behalf of the ASPREE investigator group. Psychometric properties of a short form of the Center for Epidemiologic Studies Depression (CES-D-10) scale for screening depressive symptoms in healthy community dwelling older adults. General Hospital Psychiatry 2018; 51:118-125, doi: 10.1016/j.genhosppsych.2017.08.002.

2017-2015

• McNeil JJ, Woods RL, Nelson MR, Murray AM, Reid CM, Kirpach B, Storey E, Shah RC, Wolfe R, Tonkin AM, Newman AB, Williamson JD, Lockery JE, Margolis KL, Ernst ME, Abhayaratna WP, Stocks N, Fitzgerald SM, Trevaks RE, Orchard SG, Beilin LJ, Donnan GA, Gibbs P, Johnston CI, Grimm RH, on behalf of the ASPREE investigator group. Baseline Characteristics of Participants in the ASPREE (ASPirin in Reducing Events in the Elderly) Study. J Gerontol A Biol Sci Med Sci 2017; Oct 12, Vol. 00, No. 00, 1–8, doi:10.1093/gerona/glw342.
• Ward SA, Raniga P, Ferris NJ, Woods RL, Storey E, Bailey MJ, Brodtmann A, Yates PA, Donnan GA, Trevaks RE, Wolfe R, Egan GF, McNeil JJ; (Joint Senior authorship), on behalf of the ASPREE investigator group. ASPREE-NEURO study protocol: A randomized controlled trial to determine the effect of low-dose aspirin on cerebral microbleeds, white matter hyperintensities, cognition, and stroke in the healthy elderly. Int J Stroke 2017; 12(1):108-113, doi:10.1177/1747493016669848.
• Lacaze P, Winship I, McNeil J. Penetrance and the Healthy Elderly. Genet Test Mol Biomarkers 2017; Nov 21(11):637-640, doi: 10.1089/gtmb.2017.0126 [epub 2017 Sept. 6].
• Robman L, Guymer R, Woods RL, Ward SA, Wolfe R, Phung J, Hodgson L, Makeyeva G, Aung KZ, Gilbert T, Lockery JE, Le-Pham Y, Orchard S, Storey E, Abhayaratna W, Reid D, Ernst ME, Nelson MR, Reid C, McNeil, JJ. Age-related macular degeneration in a randomized controlled trial of low-dose aspirin: Rationale and study design of the ASPREE-AMD study. Contemporary Clinical Trials Communications 2017; Vol.6, pp.105-114, doi:10.1016/j.conctc.2017.03.005.
• Lacaze P, Ryan J, Woods RL, Winship I, McNeil JJ. Pathogenic variants in the healthy elderly: unique ethical and practical challenges. Journal of Medical Ethics, 2017; Vol. 43(10), p.714, doi: 10.1136/medethics-2016-103967.
• Lacaze P, Woods RL, Zoungas S, McNeil JJ. The genomic potential of the Aspirin in Reducing Events in the Elderly and Statins in Reducing Events in the Elderly studies. Internal medicine Journal 2017; Vol.47(4), pp.461-463, doi.org/10.1111/imj.13384.
• Eisen DP, Moore EM, Leder K, Lockery JE, McBryde ES, McNeil JJ, Pilcher D, Wolfe R, Woods RL. AspiriN To Inhibit SEPSIS (ANTISEPSIS) randomised controlled trial protocol. BMJ Open 2017;7:e013636, doi: 10.1136/bmjopen-2016-013636.
• Berk M, Woods RL, Nelson MR, Shah RC, Reid CM, Storey E, Fitzgerald SM, Lockery JE, Wolfe R, Mohebbi M, Murray AM, Kirpach B, Grimm R, McNeil JJ. ASPREE-D: Aspirin for the prevention of depression in the elderly. International Psychogeriatrics 2016, doi:10.1017/S104161021600079X.
• Lowthian JA, Britt CJ, Rance G, Lin FR, Woods RL, Wolfe R, Nelson MR, Dillon HA, Ward S, Reid CM, Lockery JE, Nguyen TT, McNeil JJ, Storey E. Slowing the progression of age-related hearing loss: Rationale and study design of the ASPIRIN in HEARING, retinal vessels imaging and neurocognition in older generations (ASPREE-HEARING) trial. Contemp Clin Trials 2015; 46; 60-66, doi: 10.1016/j.cct.2015.11.014.
• Barker AL, McNeil JJ, Seeman E, Ward SA, Sanders KM, Khosla S, Cumming RG, Pasco JA, Bohensky MA, Ebeling PR, Woods RL, Lockery JE, Wolfe R, Talevski J, and the ASPREE Investigator Group. A randomised controlled trial of low-dose aspirin for the prevention of fractures in healthy older people: protocol for the ASPREE-Fracture substudy. Inj Prev. 2015; pii: injuryprev-2015-041655, doi: 10.1136/injuryprev-2015-041655 [epub ahead of print]. PMID: 26002770

2014-2010

• COMMENTARY Chong EW, Guymer RH, Robman LD. Does aspirin increase the risk of age-related macular degeneration? Expert Opinion on Drug Safety 2014; 13:691-3, doi: 10.1517/14740338.2014.914169.
• ASPREE Investigator Group. Study design of ASPirin in Reducing Events in the Elderly (ASPREE): a randomized, controlled trial. Contemporary Clinical Trials 2013; 36: 555–564, doi: org/10.1016%2Fj.cct.2013.09.014.
• COMMENTARY Nelson MR. General practice-based clinical trials. Perspectives, Med J Aust 2013; 198 (3), doi: 10.5694/mja12.11061.
• Reid CM, Storey E, Wong TY, Woods RL, Tonkin A, Wang JJ, Kam A, Janke A, Essex R, Abhayaratna WP, Budge MM, on behalf of the ASPREE Study Group. Aspirin for the prevention of cognitive decline in the elderly: rationale and design of a neuro-vascular imaging study (ENVIS-ion). BMC Neurol. 2012; 12:3, doi: 10.1186/1471-2377-12-3.
• Linden MD, Tran HA, Woods RL, Tonkin AM. High platelet reactivity and antiplatelet therapy resistance. Seminars in Thrombosis and Hemostasis 2012; 38(2):200-12, doi: 10.1055/s-0032-1301417.
• Ward SA, Demos L, Workman B, McNeil JJ. Aspirin for primary prevention of cardiovascular events in the elderly: current status and future directions. Drugs Aging 2012; Apr. 1;29(4):251-8, doi.org/10.2165/11599030-000000000-00000.

2009-1990

• EDITORIAL: Woods RL, Tonkin AM, Nelson MR, Britt HC, Reid CM. Should aspirin be used for the primary prevention of cardiovascular disease in people with diabetes? Med J Aust. 2009; 190:614-5 PMID:19485837
• Nelson MR, Reid CM, Ames DA, Beilin LJ, Donnan GA, Gibbs P, Johnston CI, Krum H, Storey E, Tonkin A, Wolfe R, Woods R, McNeil JJ. Feasibility of conducting a primary prevention trial of low-dose aspirin for major adverse cardiovascular events in older people in Australia: results from the ASPirin in Reducing Events in the Elderly (ASPREE) pilot study. Med J Aust. 2008; 189:105-109, doi.org/10.5694/j.1326-5377.2008.tb01932.x.  PMID:18637782
• Nelson MR, Liew D, Bertram M, Vos T. Epidemiological modelling of routine use of low-dose aspirin in Australia for the primary prevention of coronary heart disease and stroke in those aged 70 years and above. BMJ 2005; 330:1306-1308, doi: 10.1136/bmj.38456.676806.8F.
• CONFERENCE PROCEEDINGS: Nelson MR, Reid CM, Johnstone CI, Krum H, Storey E, Tonkin A, Beilin LJ, Donnan GA, McNeil JJ.  After ANBP2 – ASPREE  Clinical And Experimental Pharmacology And Physiology, Melbourne, Australia 2003; Vol.30(7), pp.A59-A59.
• ASPREE Study Group. Nelson MR, Reid CM, Beilin LJ, Donnan GA, Johnston CI, Krum H, Storey E, Tonkin AM, McNeil JJ.  Rationale for a primary prevention trial in the elderly of low dose aspirin for the prevention of major adverse cardiovascular events and vascular dementia in Australian general practice.  ASPirin in Reducing Events in the Elderly (ASPREE). J Drugs and Aging 2003; 20(12):897-903, doi: 10.2165/00002512-200320120-00004.
• Nelson M, Reid C, Beilin L, Donnan G, Johnston C, Krum H, Storey E, Tonkin A, McNeil J; Aspirin in Reducing Events in the Elderly (ASPREE) Study Group,. Rationale for a trial of low-dose aspirin for the primary prevention of major adverse cardiovascular events and vascular dementia in the elderly: Aspirin in Reducing Events in the Elderly (ASPREE). Drugs Aging. 2003;20(12):897-903, doi: 10.2165/00002512-200320120-00004 PMID: 14565783.
• Silagy CA, McNeil JJ, Donnan GA, Tonkin AM, Worsam B, Campion K. The PACE pilot study: 12-month results and implications for future primary prevention trials in the elderly. (Prevention with low-dose Aspirin of Cardiovascular disease in the Elderly). J Am Geriatr Soc. 1994; 42(6):643-64, doi.org/10.1111/j.1532-5415.1994.tb06864.x.
• Silagy CA, McNeil JJ, Donnan GA, Tonkin AM, Worsam B, Campion K. Adverse effects of low-dose aspirin in a healthy elderly population. Clin Pharmacol Ther, 1993; 54(1):84-89, doi:10.1038/clpt.1993.115.
• Silagy CA, McNeil JJ, Bulpitt CJ, Donnan GA, Tonkin AM, Worsam B. Rationale for a primary prevention study using low-dose aspirin to prevent coronary and cerebrovascular disease in the elderly. J Am Geriatr Soc. 1991; 39(5):484-491, doi.org/10.1111/j.1532-5415.1991.tb02494.x.
• Campion K, Silagy CA, McNeil JJ, Donnan GA, Tonkin AM, Worsam B. Comparison of recruitment strategies for a large-scale multicentred clinical trial in the elderly. Community Health Stud, 1990; 14(4):400, doi: 10.1016/0895-4356(91)90013-y.