![\"\"](\"\/wp-content\/uploads\/sites\/3\/2021\/07\/halgatewood-com-iPl3q-gEGzY-unsplash.ed_.jpg\")
<\/h2>\n\u00a0<\/h2>\n\u00a0<\/h2>\nWhy is aspirin so special?<\/h2>\n<\/div>\n<\/div>\n
\u00a0<\/h2>\nWhy is aspirin so special?<\/h2>\n<\/div>\n<\/div>\n
Aspirin is one of the most widely used and affordable medications in the world. It has been used in medical practice since the late 1890\u2019s. Such is the importance of aspirin that it continues to be the subject of hundreds of published research studies each year.<\/p>\n
\u00a0<\/h3>\nHow does aspirin work?<\/h3>\n
Aspirin has two main actions in the body:<\/p>\n
- \n
- Prevents blood platelets from clumping together to form a blood clot (‘blood thinner effect’). which can prolong the time it takes for bleeding to stop.<\/li>\n
- Higher doses of aspirin reduces the production in the body of chemicals called ‘prostaglandins\u2019, thereby reducing inflammation, pain, and fever.<\/li>\n<\/ul>\n
\u00a0<\/h3>\n
Uses of aspirin<\/h3>\n
- \n
- Low-dose aspirin (100 mg) is used after a first heart attack, angina or stroke to prevent a second or third similar event. This is known as \u2018secondary prevention.\u2019<\/li>\n
- Higher doses of aspirin (300 \u2013 500 mg) provides temporary relief of pain, inflammation and fever.<\/li>\n<\/ul>\n
\u00a0<\/h4>\n
Side effects of aspirin<\/h3>\n
All medications have the potential to cause adverse effects, and aspirin is no exception. Aspirin belongs to a class of drugs called non-steroidal anti-inflammatory drugs (NSAID) which may interact with several other medications.<\/p>\n
- \n
- Aspirin\u2019s side effects are more commonly seen in older adults and in those receiving higher doses.<\/li>\n
- Aspirin delays the ability of the blood to clot and block the leakage of blood from ruptured blood vessels.<\/li>\n
- Aspirin reduces the effectiveness of the protective barrier in the stomach which may lead to bleeding from the stomach wall. This video<\/a> explains how aspirin may cause bleeding in the stomach.<\/li>\n
- More information about possible side-effects of low-dose aspirin and drug interactions<\/a> is here<\/a> and here<\/a>.<\/li>\n<\/ul>\n
Note: it is important to talk to your Primary Care Provider before starting daily low-dose aspirin even though you can buy it without a prescription.<\/em><\/p>\n
\n
\n<\/div>\n<\/p>\n
<\/p>\n
Fun facts about Aspirin<\/h2>\n
<\/p>\n
![\"\"](\"\/wp-content\/uploads\/sites\/3\/2021\/07\/iStock-173942298.jpg\")
<\/h2>\n<\/p>\n
- \n
- The melting point of aspirin (acetylsalicylic acid, ASA) is 275 \u00b0F.<\/li>\n
- In 1950, aspirin was entered into the Guinness Book of Records as the highest-selling drug product.<\/li>\n
- Approximately 25,000 scientific articles about aspirin and a projected one trillion aspirin pills have been consumed since it arrived on the market<\/a>.<\/li>\n
- Approximately 40,000 tons of aspirin are produced annually worldwide<\/a>.<\/li>\n
- Adding aspirin to water in a vase will make cut flowers last longer. The effect is attributable to salicylic acid, which as a messenger substance plays an important role in plants\u2019 survival.<\/li>\n
- Before 1904, Bayer sold aspirin to pharmacies as a fine, white powder in bottles.<\/li>\n
- After becoming world famous for developing aspirin, Felix Hoffmann disappeared completely from the public eye. After retiring in 1928, he moved to Switzerland where he lived in seclusion until his death in 1946.<\/li>\n
- In 2002, Felix Hoffmann was inducted into the US National Inventors Hall of Fame.<\/a><\/li>\n
- After aspirin was developed in 1897, it was around 70 years before British scientist Professor Sir John R. Vane made the Nobel Prize winning discovery that it worked by inhibiting prostaglandins (pain messenger chemicals).<\/li>\n
- Aspirin went into space, as part of the on-board medicine kit on all of the Apollo rockets that NASA sent to the moon \u2013 both the orbital lunar flights in 1968\/69 and the seven moon landings from 1969 to 1972 (Apollo 11 to Apollo 17).<\/li>\n
- Salicylic acid is found in certain vegetables, fruits, nuts, seeds and herbs in various amounts. Acetyl salicylic acid in aspirin, is a modified version of salicylic acid.<\/li>\n<\/ul>\n
Sources and further reading:\u00a0History of Aspirin<\/a>, Pharmaceutical Journal,<\/a> Aspirin timeline<\/a>, Wikipedia<\/a><\/p>\n
<\/p>\n
[\/et_pb_text][\/et_pb_column_inner][\/et_pb_row_inner][et_pb_row_inner admin_label=”INFORMATION DOCUMENTS” module_class=”tab-content” _builder_version=”4.16″ _module_preset=”default” max_width=”840px” global_colors_info=”{}”][et_pb_column_inner saved_specialty_column_type=”2_3″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_text admin_label=”Information documents” _builder_version=”4.19.3″ header_2_font=”|600|||||||” header_2_font_size=”32px” background_layout=”dark” header_2_font_size_tablet=”28px” header_2_font_size_phone=”24px” header_2_font_size_last_edited=”on|desktop” locked=”off” global_colors_info=”{}”]<\/p>\n
Information documents<\/h2>\n
[\/et_pb_text][et_pb_text admin_label=”ASPREE and XT brochures” _builder_version=”4.19.3″ _module_preset=”default” link_text_color=”#c9a700″ background_layout=”dark” global_colors_info=”{}”]<\/p>\n
ASPREE Brochures<\/h3>\n
- \n
- ASPREE Brochure ENGLISH\u00a0<\/a><\/li>\n
- ASPREE Brochure SPANISH<\/a><\/li>\n
- ASPREE-XT Brochure\u00a0<\/a><\/li>\n<\/ul>\n
[\/et_pb_text][\/et_pb_column_inner][\/et_pb_row_inner][et_pb_row_inner admin_label=”PARTICIPANT NEWSLETTERS” module_class=”tab-content” _builder_version=”4.16″ _module_preset=”default” max_width=”840px” global_colors_info=”{}”][et_pb_column_inner saved_specialty_column_type=”2_3″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_text admin_label=”Listed” _builder_version=”4.20.4″ text_text_color=”#ffffff” link_text_color=”#c9a700″ header_2_font=”|600|||||||” header_2_font_size=”32px” background_layout=”dark” hover_enabled=”0″ header_2_font_size_tablet=”28px” header_2_font_size_phone=”24px” header_2_font_size_last_edited=”on|desktop” locked=”off” global_colors_info=”{}” sticky_enabled=”0″]<\/p>\n
Newsletters<\/h2>\n
The newsletters help keep you and the general community up-to-date on the ASPREE project \u2013 from study progress to news stories, and reminders. If you have any suggestions or ideas for future newsletter content, please email Brenda Kirpach at: BKirpach@bermancenter.org <\/a>Thank you!<\/p>\n
\u00a0<\/h4>\n
View past editions of the ASPREE participant newsletter:<\/h4>\n
- \n
- ASPREE-XT Newsletter Summer Vol 22, 2024<\/a><\/li>\n
- ASPREE-XT Newsletter Winter Vol 21, 2024<\/a><\/li>\n
- ASPREE-XT Newsletter Summer Vol 20, 2023<\/a><\/li>\n
- ASPREE-XT Newsletter Winter Vol 19, 2023<\/a><\/li>\n
- ASPREE-XT Newsletter Summer Vol 18, 2022<\/a><\/li>\n
- ASPREE-XT Newsletter Winter Vol 17, 2021<\/a><\/li>\n
- ASPREE-XT Newsletter Winter Vol 16, 2021<\/a><\/li>\n
- ASPREE-XT Newsletter Spring Vol 15, 2020<\/a><\/li>\n
- ASPREE Newsletter Summer Vol 14, 2017<\/a><\/li>\n
- ASPREE Newsletter Winter Vol 13, 2017<\/a><\/li>\n
- ASPREE Newsletter Summer Vol 12, 2016<\/a><\/li>\n
- ASPREE Newsletter Winter Vol 11, 2016<\/a><\/li>\n
- ASPREE Newsletter Summer Vol 10, 2015<\/a><\/li>\n
- ASPREE Newsletter Winter Vol 9, 2014<\/a><\/li>\n
- ASPREE Newsletter Summer Vol 8, 2014<\/a><\/li>\n<\/ul>\n
[\/et_pb_text][\/et_pb_column_inner][\/et_pb_row_inner][\/et_pb_column][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”4.16″ _module_preset=”default” min_height=”100px” height=”100px” max_height=”100px” custom_margin=”-1px||-1px||false|false” custom_padding=”0px||0px||false|false” locked=”off” global_colors_info=”{}”][et_pb_row column_structure=”1_2,1_2″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_column type=”1_2″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_text admin_label=”Dated” _builder_version=”4.20.4″ _module_preset=”default” global_colors_info=”{}”]<\/p>\n
Page updated: August 15, 2023<\/p>\n
[\/et_pb_text][\/et_pb_column][et_pb_column type=”1_2″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”4.16″ custom_padding=”90px||70px||false|false” border_width_top=”1px” border_color_top=”#cecece” saved_tabs=”all” locked=”off” global_colors_info=”{}”][et_pb_row use_custom_gutter=”on” _builder_version=”4.16″ global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ global_colors_info=”{}”][et_pb_text _builder_version=”4.16″ _module_preset=”d100a70a-4a1b-4c0a-852d-deb7ebdb8d36″ header_font=”|600||on|||||” header_text_align=”left” header_2_font=”|600||on|||||” header_2_text_align=”left” header_2_font_size=”32px” text_orientation=”center” custom_margin=”||0px||false|false” header_2_font_size_tablet=”28px” header_2_font_size_phone=”24px” header_2_font_size_last_edited=”on|desktop” global_colors_info=”{}”]<\/p>\n
NEWS FOR PARTICIPANTS<\/h2>\n
[\/et_pb_text][et_pb_blog fullwidth=”off” posts_number=”3″ include_categories=”15″ show_author=”off” show_date=”off” show_categories=”off” masonry_tile_background_color=”rgba(0,0,0,0)” _builder_version=”4.20.4″ header_level=”h4″ header_font=”|600|||||||” header_font_size=”22px” custom_margin=”||40px||false|false” header_font_size_tablet=”20px” header_font_size_phone=”18px” header_font_size_last_edited=”on|desktop” border_width_all=”0px” global_colors_info=”{}”][\/et_pb_blog][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"
FOR PARTICIPANTS Thanks to the generosity of 19,114 older adults, ASPREE is one of the most significant research projects of our time.\u00a0 Your contribution matters to the health of future generations.ASPREE The ASPREE Clinical Trial (completed) The follow-up ASPREE-XT Study (current) \u2192\u00a0Update your details \u2192 About Participants \u2192\u00a0FAQs, newsletters and more \u2192\u00a0Latest news \u2192\u00a0Contact […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"_links":{"self":[{"href":"https:\/\/aspree.org\/usa\/wp-json\/wp\/v2\/pages\/272"}],"collection":[{"href":"https:\/\/aspree.org\/usa\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/aspree.org\/usa\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/aspree.org\/usa\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/aspree.org\/usa\/wp-json\/wp\/v2\/comments?post=272"}],"version-history":[{"count":72,"href":"https:\/\/aspree.org\/usa\/wp-json\/wp\/v2\/pages\/272\/revisions"}],"predecessor-version":[{"id":2888,"href":"https:\/\/aspree.org\/usa\/wp-json\/wp\/v2\/pages\/272\/revisions\/2888"}],"wp:attachment":[{"href":"https:\/\/aspree.org\/usa\/wp-json\/wp\/v2\/media?parent=272"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
- ASPREE-XT Newsletter Winter Vol 21, 2024<\/a><\/li>\n
- ASPREE Brochure SPANISH<\/a><\/li>\n
- Approximately 40,000 tons of aspirin are produced annually worldwide<\/a>.<\/li>\n
- More information about possible side-effects of low-dose aspirin and drug interactions<\/a> is here<\/a> and here<\/a>.<\/li>\n<\/ul>\n