{"id":5550,"date":"2014-08-07T12:11:05","date_gmt":"2014-08-07T12:11:05","guid":{"rendered":"https:\/\/aspree.org\/aus\/?p=5550"},"modified":"2021-08-23T01:53:27","modified_gmt":"2021-08-23T01:53:27","slug":"aspirin-may-reduce-cancer-risk-in-middle-aged-benefit-in-older-people-unknown","status":"publish","type":"post","link":"https:\/\/aspree.org\/aus\/aspirin-may-reduce-cancer-risk-in-middle-aged-benefit-in-older-people-unknown\/","title":{"rendered":"Aspirin May Reduce Cancer Risk in Middle-Aged; Benefit in Older People Unknown"},"content":{"rendered":"\n<h2 class=\"wp-block-heading\">Lack of data underscores importance of ASPREE trial<\/h2>\n\n\n\n<p><\/p>\n\n\n\n<p>A large scientific review revealed that aspirin protected people aged 50-65 against gastrointestinal cancer, but was unable to determine cancer benefits for those aged over 70.<\/p>\n\n\n\n<p>International researchers, who analysed around 200 papers, explained there was \u2018uncertainty\u2019 about the balance of benefits versus the risk of daily low-dose aspirin in older adults.<\/p>\n\n\n\n<p>\u201cFor example the balance of benefit-harm in usage above the age of 70 may be different since bleeding events become more common and serious after this age, but the cancer rates also become higher,\u201c researchers wrote. \u201c(The) Ongoing ASPREE trial may help address the question of low-dose aspirin use in elderly.\u201d<\/p>\n\n\n\n<div class=\"wp-block-image\"><figure class=\"alignleft size-large is-resized\"><img decoding=\"async\" loading=\"lazy\" src=\"https:\/\/aspree.org\/wp-content\/uploads\/sites\/2\/2021\/03\/Prof-Mark-Nelson.ed_.jpg\" alt=\"Mature aged white man, glasses and grey hair dressed in a pale shirt and tie in front of a grey\/brown background.\" class=\"wp-image-5457\" width=\"432\" height=\"431\" \/><\/figure><\/div>\n\n\n\n<p>Professor Mark Nelson, (pictured left) a <a href=\"\/aus\/about-us\/\">chief investigator<\/a> to the ASPREE trial in Tasmania, said the review highlighted the lack of available research in the elderly and the importance of the ASPREE to answer this question.<\/p>\n\n\n\n<p>\u201cPeople over the age of 70 should not be looked upon as middle-aged individuals. Much like we wouldn\u2019t assume medication used in children is the same as when used in adults.  Our bodies change with age: our susceptibility to certain diseases change with age, as does our response to medication,\u201d said Prof Nelson.<\/p>\n\n\n\n<p>\u201cASPREE is the only trial in the world to determine whether healthy older people should or should not take aspirin to prevent diseases such as cancer, dementia and cardiovascular disease.\u201d<\/p>\n\n\n\n<p>The review, which was published in the <a href=\"https:\/\/dash.harvard.edu\/bitstream\/handle\/1\/14351325\/4269341.pdf?sequence=1&amp;isAllowed=y\" target=\"_blank\" rel=\"noreferrer noopener\">Annals of Oncology<\/a> journal, found that middle-aged people needed to take aspirin between 5 and 10 years to see the cancer benefit.<\/p>\n\n\n\n<p>\u201cWhile this study is interesting because it demonstrates a link between aspirin and cancer, it supports large randomised studies such as ASPREE to provide more robust evidence relevant to older Australians,\u201d said Prof Nelson.<\/p>\n\n\n\n<p>Researchers recommend anyone considering commencing daily aspirin or changing their aspirin regime, should speak to their GP first.<\/p>\n\n\n\n<pre class=\"wp-block-preformatted\"><em>Updated 25.03.2021<\/em><\/pre>\n\n\n\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"<p>A large scientific review of aspirin and cancer was unable to determine cancer benefits for those aged over 70, underscoring the importance of the ASPREE trial.<\/p>\n","protected":false},"author":2,"featured_media":5090,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"off","_et_pb_old_content":"","_et_gb_content_width":"1200","footnotes":""},"categories":[17,18,16],"tags":[28,47,74],"_links":{"self":[{"href":"https:\/\/aspree.org\/aus\/wp-json\/wp\/v2\/posts\/5550"}],"collection":[{"href":"https:\/\/aspree.org\/aus\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/aspree.org\/aus\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/aspree.org\/aus\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/aspree.org\/aus\/wp-json\/wp\/v2\/comments?post=5550"}],"version-history":[{"count":5,"href":"https:\/\/aspree.org\/aus\/wp-json\/wp\/v2\/posts\/5550\/revisions"}],"predecessor-version":[{"id":7272,"href":"https:\/\/aspree.org\/aus\/wp-json\/wp\/v2\/posts\/5550\/revisions\/7272"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/aspree.org\/aus\/wp-json\/wp\/v2\/media\/5090"}],"wp:attachment":[{"href":"https:\/\/aspree.org\/aus\/wp-json\/wp\/v2\/media?parent=5550"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/aspree.org\/aus\/wp-json\/wp\/v2\/categories?post=5550"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/aspree.org\/aus\/wp-json\/wp\/v2\/tags?post=5550"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}